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The American Journal of Digestive Diseases

, Volume 4, Issue 11, pp 707–712 | Cite as

Studies in mucous membrane hypersensitiveness

III. The allergic reaction of the passively sensitized rectal mucous membrane
  • Irving Gray
  • Matthew Walzer
Article

Conclusions

1. The rectal mucous membrane can be passively and locally sensitized with human reagin-bearing sera.

2. The allergic reaction can be induced by either the oral or the rectal administration of the antigen.

3. The allergic reaction consists of edema, hyperemia, and increased mucous secretion.

4. Subjective symptoms, such as pruritis, burning, a sense of fullness, and a desire to empty the bowel, are commonly associated with the allergic reaction and vary with its location.

5. The allergic reaction in the sensitized mucous membrane of the gastro-intestinal tract may be induced by antigen which is in direct contact with it or by absorbed antigen which reaches it via the circulation or by both.

Keywords

Allergic Reaction Food Allergy Mucous Membrane Subjective Symptom Rectal Mucous Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Walzer, M., Sherman, H. and Feldman, L.: Studies in Mucous Membrane Hypersensitiveness. I. Passive Local Sensitization of the Ophthalmic Mucous Membrane.Jour. of Allergy, 6:215, 1935.CrossRefGoogle Scholar
  2. 2.
    Sherman, H., Kaplan, C. and Walzer, M.: Studies in Mucous Membrane Hypersensitiveness. II. Passive Local Sensitization of the Nasal Mucous Membrane. In press.Google Scholar
  3. 3.
    Gray, I. and Walzer, M.: Studies in Absorption of Undigested Proteins in Human Beings. VI. The Absorption of Unaltered Protein from the Abnormal Gastro-Intestinal Tract.Amer. J. Digest. Dis. and Nutrit., 3:403, 1936.Google Scholar
  4. 4.
    Walzer, M.: Studies in Absorption of Undigested Proteins in Human Beings. I. A Simple Direct Method of Studying the Absorption of Undigested Protein.Jour. of Imm., 14:144, 1927.Google Scholar
  5. 5.
    Walzer, A. and Walzer, M.: Urticaria. II. The Experimental Wheal Produced on Normal Skin Through Internal Channels.Arch. of Derm. and Syph., 17:659, 1928.Google Scholar

Copyright information

© Springer-Verlag 1937

Authors and Affiliations

  • Irving Gray
    • 1
  • Matthew Walzer
    • 1
  1. 1.Brooklyn

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