International Journal of Hematology

, Volume 76, Issue 5, pp 471–473

Atypical Presentations of Thrombotic Thrombocytopenic Purpura

Case Report

DOI: 10.1007/BF02982814

Cite this article as:
O’Brien, T.E. & Crum, E.D. Int J Hematol (2002) 76: 471. doi:10.1007/BF02982814


Thrombotic thrombocytopenic purpura (TTP) usually presents in a fulminant fashion with marked hematologic abnormalities often associated with fever and neurologic and renal abnormalities. Two cases of TTP are reported in which neurologic deficits were initially the dominant findings, followed weeks later by the pronounced hematologic manifestations. Young patients with unexplained neurologic findings, even if there is only minimal anemia or thrombocytopenia, should be monitored for subsequent manifestations of TTP so that treatment may be instituted promptly. Int J Hematol. 2002;76:471-473.

Key words

Thrombotic thrombocytopenic purpura Neurologic deficits 

Copyright information

© The Japanese Society of Hematology 2002

Authors and Affiliations

  1. 1.Division of Hematology/Oncology, Department of MedicineMetroHealth Medical Center, School of Medicine, Case Western Reserve UniversityCleveland, OhioUSA

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