International Journal of Hematology

, Volume 74, Issue 1, pp 9–17

Regulation of Hematopoiesis by Chemokine Family Members

Progress in hematology

Abstract

Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells.

Key words

Chemokines Stem/progenitor cells Proliferation Survival Migration/homing 

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Copyright information

© The Japanese Society of Hematology 2001

Authors and Affiliations

  1. 1.Department of Microbiology and Immunology and the Walther Oncology CenterIndiana University School of Medicine and the Walther Cancer InstituteIndianapolis, IndianaUSA
  2. 2.Walther Oncology CenterIndiana University School of MedicineIndianapolisUSA

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