Journal of Genetics

, 31:317 | Cite as

The rate of spontaneous mutation of a human gene

  • J. B. S. Haldane


The rate of mutation at which the gene for haemophilia appears in the population of London is estimated at about once in 50,000 human life cycles. There are probably two distinct allelomorphs at the same locus, the milder type arising less frequently by mutation than the severe type.


Mutation Rate Spontaneous Mutation Autosomal Recessive Heterozygous Female Dysostosis 
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Copyright information

© Indian Academy of Sciences 1935

Authors and Affiliations

  • J. B. S. Haldane

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