Synthesis of praziquantel derivatives and theirin vitro activity against adultClonorchis sinensis

  • Choong Sup Kim
  • Duk Young Min
Research Articles


Several praziquantel derivatives have been prepared by the acylation of compound5, and examined on their biological activityin vitro against adultClonorchis sinensis collected from rabbits infected with metacercariae which was isolated fromPseudorasbora parva, a second intermediate host, captured in Nakdong river in Korea.

Key words

Praziquantel derivatives Anthelmintic activity Clonorchis sinensis 

References Cited

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Copyright information

© The Pharmaceutical Society of Korea 1998

Authors and Affiliations

  • Choong Sup Kim
    • 1
  • Duk Young Min
    • 2
  1. 1.Division of Applied ScienceKorea Institute of Science & TechnologySeoulKorea
  2. 2.Department of Parasitology, College of MedicineHanyang UniversitySeoulKorea

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