Archives of Pharmacal Research

, 21:744

Synthesis of praziquantel derivatives and theirin vitro activity against adultClonorchis sinensis

  • Choong Sup Kim
  • Duk Young Min
Research Articles

DOI: 10.1007/BF02976769

Cite this article as:
Kim, C.S. & Min, D.Y. Arch. Pharm. Res. (1998) 21: 744. doi:10.1007/BF02976769


Several praziquantel derivatives have been prepared by the acylation of compound5, and examined on their biological activityin vitro against adultClonorchis sinensis collected from rabbits infected with metacercariae which was isolated fromPseudorasbora parva, a second intermediate host, captured in Nakdong river in Korea.

Key words

Praziquantel derivatives Anthelmintic activity Clonorchis sinensis 

Copyright information

© The Pharmaceutical Society of Korea 1998

Authors and Affiliations

  • Choong Sup Kim
    • 1
  • Duk Young Min
    • 2
  1. 1.Division of Applied ScienceKorea Institute of Science & TechnologySeoulKorea
  2. 2.Department of Parasitology, College of MedicineHanyang UniversitySeoulKorea
  3. 3.Biochemicals Research Center Korea Institute of Science and TechnologySeoulKorea

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