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Archives of Pharmacal Research

, Volume 25, Issue 2, pp 154–157 | Cite as

Antimicrobial constituents of foeniculum vulgare

  • Yong Soo Kwon
  • Won Gyu Choi
  • Won Jun Kim
  • Woo Kyung cKim
  • Myong Jo Kim
  • Won Hee Kang
  • Chang Min Kim
Research Articles Medicinal Chemistry & Natural Products

Abstract

A phenyl propanoid derivative, dillapional(1) was found to be a antimicrobial principle of the stems ofFoeniculum vulgare (Umbelliferae) with MIC values of 125, 250 and 125/ againstBacillus subtilis, Aspergillus niger andCladosporium cladosporioides, respectively. A cou-marin derivative, scopoletin(2) was also isolated as marginally antimicrobial agent along with inactive compounds, dillapiol(3), bergapten(4), imperatorin(5) and psolaren(6) from this plant. The isolates 1-6 were not active against the Escherichia coli.

Key words

Foeniculum vulgare Dillapional Scopoletin Dillapiol Bergapten Imperatorin Psolaren Antimicrobial activity 

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References

  1. Ceska, O., Chaudgary, S. K., Warrington, P. J., Ashwood-Smith, M. J., Photoactive furocoumarins in fruits of some umbel-lifers.Phytochemistry, 26, 165–169 (1986).CrossRefGoogle Scholar
  2. Elgamal, M. H. A., Elewa, N. H., Elkhrisy, E. A. M. and Duddeck, H., 13C NMR chemical shift and carbon-proton coupling constants of some furocoumrins and furochromones.Phytochemistry, 18, 139–143 (1979).CrossRefGoogle Scholar
  3. Harkar, S., Razden, T. K., Waight, E. S., Steroids, chromone and coumrins fro.Angelica officinalis. Phytochemistry, 23, 419–426 (1984).CrossRefGoogle Scholar
  4. Kim, C. M., Sin, M. K., Lee, K. S. and Ahn, D. K., The dictionary of Chinese medicines, Jungdam press, Seoul, pp. 6597–6604, 1997.Google Scholar
  5. Lee, K. H. and Soine, T. O., Coumain: Spectral studies on some linear furocoumarins,J. Pharm. Sci., 58, 681–683 (1969).PubMedCrossRefGoogle Scholar
  6. Ono, M., Ito, Y., Ishikawa, T., Kitajima, J., Tanaka, Y., Niiho, Y and Nohara, T., Five new monoterpene glycosides and other compounds from Foeniculi Fructus (Fruit o.Foeniculum vulgare Miller).Chem. Pharm. Bull., 44, 337–342 (1996).Google Scholar
  7. Ono, M., Ito, Y., Kinjo, J., Yahara, S., Nohara, T. and Niiho, Y., Four new glycosides of stilbene trimer from Foeniculi Fructus (Fruit o.Foeniculum vulgare Miller).Chem. Pharm. Bull., 43, 868–871 (1995).Google Scholar
  8. Orjala, J., Erdelmeier, C. A. J., Wright, A. D., Rali, T. and Sticher, O., Five new prenylated p-hydroxybenzoic acid derivatives with antimicrobial and molluscicidal activity fro.Piper aduncum leaves. Planta Med., 59, 546–551 (1993).CrossRefGoogle Scholar
  9. Steck W. and Mazurek, M., Identification of natural coumarins by nmr spectroscopy.Lloydia, 35, 418–439 (1972).PubMedGoogle Scholar
  10. Tomar, S. S. and Mukerjee, Dillapional, a new constituent of Anethum sowa Roxb.Indian J. Chem., 20B, 723–724 (1981).Google Scholar

Copyright information

© The Pharmaceutical Society of Korea 2002

Authors and Affiliations

  • Yong Soo Kwon
    • 1
  • Won Gyu Choi
    • 1
  • Won Jun Kim
    • 1
  • Woo Kyung cKim
    • 1
  • Myong Jo Kim
    • 1
    • 2
  • Won Hee Kang
    • 1
    • 2
  • Chang Min Kim
    • 1
  1. 1.College of PharmacyKangwon National UniversityChuncheonKorea
  2. 2.College of Agricultural and Life ScienceKangwon National UniversityChuncheonKorea

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