Archives of Pharmacal Research

, Volume 21, Issue 3, pp 348–352 | Cite as

Antibacterial activity ofCamellia sinensis extracts against dental caries

  • Azmat Rasheed
  • Mujtaba Haider


Different bacteria were separated from saliva and teeth of cariogenic patients and identified by a variety of morphological and biochemical tests. Extracts of green tea strongly inhibitedEscherichia coli, Streptococcus salivarius andStreptococcus mutans. The antibacterial effect of green and black tea extracts were compared with those of amoxicillin, cephradine and eugenol.

Key words

Camellia sinensis Dental caries Antibacterial activity 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References Cited

  1. De Whalley, C. V., Rakin, S. M., Hoult, J. R. S., Jessup, W., Leake, D. S., Flavonoids inhibit the oxidative modification of low density lipoprotein by macrophages.Bio. Chem. Pharmacol., 39, 1743–50 (1990).Google Scholar
  2. Enohara, T., Yamane, K., Fujiwara, H., Naeshiro, H., Naeshiro, H., Watanabe, H., Dentifrice containing powdered tea for controlling gingivitis.Jpn. Kokai Takyo Koho JP, 07, 33, 632 (1995).Google Scholar
  3. Fujiki, H., Yoshizawa, S., Horiuchi, T., Suganuma, M., Yatsunami, J., Nishiwaki, S., Anticariogenic effect of (−) epigallocatechin gallate.Prev. Med., 2, 361–9 (1992).Google Scholar
  4. Hamdaoui, M., Hedhili, A., Doghri, T., Tritar, B., Effect of tea on iron absorption from the typical Tunisian meal conscous fed to healthy rats.Ann. Nutr. Metab., 38, 226–31 (1994).PubMedCrossRefGoogle Scholar
  5. Hashimoto, F., Kashiwada, Y., Nonaka, G., Nishioka, I., Nohara, T., Cosentno, L. M., Lee, K., Anti AIDS agents. 24. Evaluation of tea polyphenols as Anti-HIV agents.Bioorg. Med. Chem, Lett. 6, 695–700 (1996).CrossRefGoogle Scholar
  6. Hayashi, S., Natural product based deodrant.Jpn. Kokai Takyo Koho Jp 07, 194, 683 (1995).Google Scholar
  7. Hillson S.,Teeth, Cambridge University Press, Cambridge, pp. 283–300, 1990.Google Scholar
  8. Holt, J. G. and Murray, R. G. E., Identification of bacteria.Bergey's Manual of determinative bacteriology. William and Wilkins, Baltimore, Hong Kong, London, Sydney, Vol 1, 2, pp. 419–423, 1055–1063, 1984.Google Scholar
  9. Hunt, D. E., Jsandham, H. and Gilmore, R. W., Evaluation of plating media for the determination of viable microorganisms in dental plaque.Appl. Microbiology. 17, 625–626 (1969).Google Scholar
  10. Kreydiyyeh, S. I., Baydown, E. A., Churukian, Z. M., Tea extracts inhibit intestinal absorption of glucose and sodium in rats.Comp. Biochem. Physiol, C; Pharmacol; Toxicol, Endocrinol 108 C, 359–65 (1994).Google Scholar
  11. Kristoferson, K. and Bratthall, D., Transient reduction ofStreptococcus mutans interdently by cholorhexidine.Scand. J. Dent. Res., 90, 417–492 (1982).Google Scholar
  12. Ohmori, Y., Ito, M., Kishi, M., Mizutani, H., Katada, T., Konishi, H., Antiallergic constituents from Oolong tea stem.Biol. Pharm. Bull, 18, 683–6 (1995).PubMedGoogle Scholar
  13. Otake, S., Makimura, M., Kuroki, T., Nishihara, Y., Hirasawa, M., Anticaries effect of polyphenolic compounds from japanese green tea.Caries Res., 25, 438–43 (1991).PubMedCrossRefGoogle Scholar
  14. Pelczar, J. J. R. and Reid, R. D.,Microbiology (Fourth Edition) McGraw-Hill Book Company, London, Toronto, New York. pp. 107–120, 1983.Google Scholar
  15. Roth, G. I. and Calmes, R.,Oral Biology, C. V. Mosby Company, Toronto, London, pp. 341–350, 1981.Google Scholar
  16. Sagesaka, Y. M., Uemura, T., Suzuki, Y., Sugiura, T., Yoshida, M., Yamaguchi, K., Kyuki, K., Antimicrobial and anti-inflammatory actions of tea-leaf saponin.Yakugaku Zasshi. 116, 238–43 (1996).PubMedGoogle Scholar
  17. Sugyama, K., Manufacture of flavoring materials from tea leaves.Jpn. Kokai Tokyo Koho Jp, 06, 133, 729 (1994).Google Scholar
  18. Varro, E. T., Lynn, R. B., James, E. R.,Pharmacognosy (ninth edition), Lea and Febiger, Philadelphia, pp. 247, 248, 481–482, 485, 487, 1988.Google Scholar
  19. Yamane, K., Fujiwara, H., Naeshiro, H., Skin cosmetics containing tea catechin.Jpn. Kokai Tokyo Koho Jp, 07, 196, 466 (1995).Google Scholar
  20. Yeo, S.-G., Ahn, C.-W., Lee, Y.-W., Lee, T.-G., Park, Y.-H., Kim, S.-B., Antioxidative effect of tea extracts from green tea, Oolong tea and black tea.Han'guk Yongyang Siklyong Hakhoechi., 24, 299–304 (1995).Google Scholar
  21. You, -S. Q., Study on feasibility of Chinese green tea polyphenols for preventing dental caries.Chung-Hua-Kou-Chiang-Hsueh-Tsa-Chih, 28, 197–9, 254 (1993).PubMedGoogle Scholar
  22. Yu, -H., Oho, -T. Tagomori, -S. Morioka, -T. Anticariogenic effect of green tea.Fukuoka-Igaku-Zasshi., 83, 174–80 (1992).PubMedGoogle Scholar

Copyright information

© The Pharmaceutical Society of Korea 1998

Authors and Affiliations

  • Azmat Rasheed
    • 1
  • Mujtaba Haider
    • 1
  1. 1.Faculty of PharmacyUniversity of the PunjabLahorePakistan

Personalised recommendations