Archives of Pharmacal Research

, 29:786 | Cite as

Glucose-lowering effect of powder formulation of African black tea extract in KK-Ay/TaJcl diabetic mouse

  • Yoko ShojiEmail author
  • Hideki Nakashima
Articles Drug Efficacy


We observed the suppressive effect of a powder formulation of African black tea extract prepared from the leaves ofCamellia sinensis on type 2 non-insulin dependent diabetic mice, KK-Ay/TaJcl. Black tea extract significantly showed suppressive effect of the elevation of blood glucose on oral glucose tolerance test of 8 week-old KK-Ay/TaJcl mice (P<0.05). Long-term treatment with black tea extract showed significant suppression of post-prandial blood glucose and obesity (P<0.05). The weight of the intestine of mice treated with black tea extract was significantly reduced (P<0.05). From these results, African black tea used in this study showed a suppressive effect on the elevation of blood glucose during food intake and the body weight.

Key words

Black tea extract Glucose-lowering Theaflavin Tea polyphenol Adipocyte 


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Copyright information

© The Pharmaceutical Society of Korea 2006

Authors and Affiliations

  1. 1.Department of MicrobiologySt. Marianna University School of MedicineKanagawaJapan

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