Advertisement

Breast Cancer

, Volume 10, Issue 2, pp 175–178 | Cite as

Tuberculosis of axillary lymph nodes with primary breast cancer

  • Takaaki Fujii
  • Morihiko Kimura
  • Yasuhiro Yanagita
  • Tokihiro Koida
  • Hiroyuki Kuwano
Case Report

Abstract

A rare case of tuberculosis of axillary lymph nodes occurring with primary breast cancer is presented. A 78-year-old woman with no history of pulmonary tuberculosis was admitted to our hospital to undergo examination for a lump in her right breast. The tumor was in the upper outer quadrant of the right breast. On palpation, the tumor was 1.2 cm in diameter and axillary lymph node swelling was noted. Mammography disclosed a spiculated mass and swelling and calcification of the axillary lymph nodes. Sonography showed an irregular hypoechoic mass in the right breast and lymph node swelling in the right axilla, indicating breast cancer with axillary lymph nodes metastases. Chest X-ray showed clustered calcifications in the right axilla and a granular shadow in the right upper lobe. Breast conserving therapy was carried out. Invasive papillotubular carcinoma of the right breast and granulomas with calcification of lymph nodes, compatible with tuberculosis, was diagnosed. Tubercle bacillis were detected by culture of lymph nodes. This case suggests that X-ray is useful for diagnosing lymph node tuberculosis. Lymph node tuberculosis should be suspected when lymph node swelling is noted and X-ray shows clustered calcifications in axillary lymph nodes.

Key words

Tuberculosis Axillary lymph node Breast cancer 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1).
    The Japanese Breast Cancer Society: General Rules for Clinical and Pathological Recording of Breast Cancer, The 13th Edition, Tokyo, 2000.Google Scholar
  2. 2).
    Das DK, Mohil RS, Kashyap V, Khan IU, Mandal AK, Gulati SM: Colloid carcinoma of the breast caner with concomitant metastasis and a tuberculous lesion in the axillary lymph nodes.Acta Cytol 36(3): 399–403, 1992.PubMedGoogle Scholar
  3. 3).
    Robinson AJ, Horne CA, Weaver A: Coexistence of axillary tuberculous lymphadenitis with lymph node metastases from a breast carcinoma.Clin Oncol (R Coll Radiol) 13(2): 144, 2001.Google Scholar
  4. 4).
    Jensenius M, Bergmann A, Ro J, Meling GI, Nyhus S, Sauer T, Scheel B: Extrapulmonary tuberculosis. An important differential diagnosis in immigrants with suspected malignancy.Tidsskr Nor laegeforen 115(27): 3365–3368, 1995.PubMedGoogle Scholar
  5. 5).
    Shimoide H, Murata Y, Kusajima K, Oishi F, Hirayama N, Takano T, Sato N: The status of extrapulmonary tuberculosis in community hospital.Kekkaku 69(8): 519–525, 1994 in Japanese.PubMedGoogle Scholar
  6. 6).
    Schneider K, Vetter W, Steurer U: Diagnosis and therapy of lymph node tuberculosis.Schweiz Rundsch Med Prax 88(4): 105–112, 1999.Google Scholar
  7. 7).
    Dandapat MC, Mishra BM, Dash SP, Kar PK: Peripheral lymph node tuberculosis: a review of 80 cases.Br J Surg 77(8): 911–912, 1990.PubMedCrossRefGoogle Scholar
  8. 8).
    Pongrac I, Roglic M, Kotarski Z: Tuberculosis of the peripheral lymph nodes.Plume Bolesti 42(l-2): 71–73, 1990.Google Scholar
  9. 9).
    Subrahmanyam M: Role of surgery and chemotherapy for peripheral lymph node tuberculosis.Br J Surg 80(12): 1547–1548, 1993.PubMedCrossRefGoogle Scholar
  10. 10).
    Hodgson TJ, Duncan JL, Rogers K: Tuberculosis: a surgical viewpoint.Ann R Coll Surg Engl 70(3): 117–119, 1988.PubMedGoogle Scholar
  11. 11).
    Shcherba BV: Problem of differential diagnosis of tuberculosis of lymph nodes and malignant neoplasms.Probl Tuberk (7–8): 19–21, 1992.Google Scholar
  12. 12).
    Radhika S, Gupta SK, Chakrabarti A, Rajwanshi A, Joshi K: Role of culture for mycobacteria in fine-needle aspiration diagnosis of tuberculous lymphadenitis.Diagn Cytopathol 5(3): 260–262, 1989.PubMedCrossRefGoogle Scholar
  13. 13).
    Dasgupta A, Ghosh RN, Poddar AK, Mukherjee C, Mitra PK, Gupta G, Ganguly U: Fine needle aspiration cytology of cervical lymphadenopathy with special reference to tuberculosis.J Indian Med Assoc 92(2): 44–46, 1994.PubMedGoogle Scholar
  14. 14).
    Sarda AK, Bal S, Singh MK, Kapur MM: Fine needle aspiration cytology as a preliminary diagnostic procedure for asymptomatic cervical lymphadenopathy.J Assoc Physicians India 38(3): 203–205, 1990.PubMedGoogle Scholar
  15. 15).
    Hsu C, Leung BS, Lau SK, Sham JS, Choy D, Engzell U: Efficacy of fine-needle aspiration and sampling of lymph nodes in 1,484 Chinese patients.Diagn Cytopathol 6(3): 154–159, 1990.PubMedCrossRefGoogle Scholar
  16. 16).
    Lau SK, Wei WI, Hsu C, Engzell UC: Fine needle aspiration biology of tuberculous cervical lymphadenopathy.Aust N Z J Surg 58(12): 947–950, 1988.PubMedCrossRefGoogle Scholar

Copyright information

© The Japanese Breast Cancer Society 2003

Authors and Affiliations

  • Takaaki Fujii
    • 1
    • 2
  • Morihiko Kimura
    • 1
  • Yasuhiro Yanagita
    • 1
  • Tokihiro Koida
    • 1
  • Hiroyuki Kuwano
    • 2
  1. 1.Department of SurgeryGunma Cancer CenterJapan
  2. 2.Department of Surgery IGunma UniversityJapan

Personalised recommendations