Breast Cancer

, 6:131 | Cite as

A case of breast cancer metastatic to the head of the pancreas

  • Tadashi Nomizu
  • Naoto Katagata
  • Takanori Matsuoka
  • Satoshi Suzuki
  • Tomonori Yabuta
  • Fumiaki Watanabe
  • Yoshio Yamaki
  • Takeo Saito
  • Atsuo Tsuchiya
  • Rikiya Abe
Case Report

Abstract

A case of breast cancer that metastasized to the head of the pancreas 6 years and 8 months after mastectomy is reported. The pancreas head metastasis was associated with general fatigue and obstructive jaundice. The serum levels of CEA, CA15-3 and NCC-ST-439, tumor markers of breast cancer, were within normal limits, but CA15-3 was immunohistochemically demonstrated in the resected metastatic lesion, in a manner similar to lobular carcinoma of the breast.

Key words

Recurrent breast cancer Metastasis to the pancreas head Obstructive jaundice Lobular carcinoma 

Abbreviations

CEA

Carcinoembryonic antigen

ER

Estrogen receptor

PgR

Progesterone receptor

X-ray

X ray photography

CT

Computed tomography

PTCD

Percutaneous transhepatic cholangiography & drainage

References

  1. 1).
    Abrams HL, Spiro R, Goldstein N: Metastases in carcinoma; Analysis of 1000 autopsied cases.Cancer 3:74–85, 1950.PubMedCrossRefGoogle Scholar
  2. 2).
    Kozuka S, Tubota M, Taki T: Pathology of metastatic cancer in the pancreas.Tan to Sui (J Biliary Tract Pancreas) 1:1531–1535, 1980 (in Japanese).Google Scholar
  3. 3).
    Pappo I, Feigin E, Uziely B,et al: Biliary and pancreatic metastases of breast carcinoma; Is surgical palliation indicated?J Surg Oncol 46:211–214, 1991.PubMedCrossRefGoogle Scholar
  4. 4).
    Mehta SA, Jagannath P, Krishnamurthy SC,et al: Isolated pancreatic metastasis from locally controlled breast cancer; A case report.Indian J Cancer 28:48–50, 1991.PubMedGoogle Scholar
  5. 5).
    Mountney J, Maury AC, Jackson AM,et al: Pancreatic metastases from breast cancer; An unusual cause of biliary obstruction.Eur J Surg Oncol 23:574–576, 1997.PubMedCrossRefGoogle Scholar
  6. 6).
    Robbins EG, Franceschi D, Barkin JS: Solitary metastatic tumors to the pancreas; A case report and review of the literature.Am J Gastroenterol 91:2414–2417, 1996.PubMedGoogle Scholar
  7. 7).
    Kopelson G, Chu AM, Doucette JA,et al: Extrahepatic biliary tract metastases fron breast cancer.Int J Radiat Oncol Biol Phys 6:497–504, 1980.PubMedGoogle Scholar
  8. 8).
    Kidney DD, Cohen AJ, Butler J: Abdominal metastases of infiltrating lobular breast carcinoma; CT and fluoroscopic imaging findings.Abdom Imaging 22:156–159, 1997.PubMedCrossRefGoogle Scholar
  9. 9).
    Watanabe F, Nomizu T, Katagata N,et al: A case of retroperitoneal metastasis of breast cancer.Jpn J Breast Cancer 13:808–812, 1998 (in Japanese with English abstract).Google Scholar
  10. 10).
    Hilkens J, Buus F, Hilgers J,et al: Monoclonal antibodies against human milkfat globule membranes detecting differentiation antigens of the mammary gland and its tumor.Int J Cancer 34:197–206, 1984.PubMedCrossRefGoogle Scholar
  11. 11).
    Kufe D, Inghirami G, Abe M: Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors.Hybridoma 3:223–231, 1984.PubMedGoogle Scholar
  12. 12).
    Nomizu T, Nihei M, Suzuki S,et al: Clinical study of CA15-3 in breast cancer as the indicator on the decision of efficacy of treatment in advanced or recurrent breast cancer.Fukushima Med J 36:427431, 1986 (in Japanese with English abstract).Google Scholar
  13. 13).
    Ohuchi N, Sato S, Akimoto M,et al: The correlation between the immunohistochemical expression of DF3 antigen and serum CA15-3 in breast cancer patients.Jpn J Surg 21:129–137, 1991.PubMedCrossRefGoogle Scholar
  14. 14).
    Nomizu T, Kanno M, Watanabe T,et al: A case of breast cancer metastatic to the pituitary gland.Breast Cancer 3:71–74, 1996.PubMedCrossRefGoogle Scholar

Copyright information

© The Japanese Breast Cancer Society 1999

Authors and Affiliations

  • Tadashi Nomizu
    • 1
    • 3
  • Naoto Katagata
    • 1
  • Takanori Matsuoka
    • 1
    • 3
  • Satoshi Suzuki
    • 1
    • 3
  • Tomonori Yabuta
    • 1
    • 3
  • Fumiaki Watanabe
    • 1
  • Yoshio Yamaki
    • 1
  • Takeo Saito
    • 2
  • Atsuo Tsuchiya
    • 3
  • Rikiya Abe
    • 3
  1. 1.Departments of SurgeryFukushima Medical UniversityFukushima
  2. 2.Departments of PathologyHoshi General Hospital Fukushima Medical UniversityFukushima
  3. 3.The Second Department of SurgeryFukushima Medical UniversityFukushima

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