Acta Endoscopica

, Volume 37, Issue 3, pp 305–313

Dépistage du cancer colorectal en 2006

  • Patricia Piront
  • E. Louis
  • J. Belaiche
  • M. Polus
Article
  • 43 Downloads

Résumé

Le cancer colorectal est un cancer fréquent dans nos pays du Nord de l’Europe; la mortalité reste élevée malgré de nombreuses et nouvelles possibilités thérapeutiques.

Le dépistage de masse, dont le but est de réduire la mortalité de ce cancer, devrait être une priorité politique à l’échelon national.

Les techniques de dépistage sont nombreuses, plus ou moins invasives mais aucune ne fait l’objet de recommandations unanimes.

A l’avenir, les progrès de la technologie médicale dans les domaines de l’imagerie, de l’endoscopie et de la biologie moléculaire devraient permettre un dépistage plus efficace tout en restant tolérable par le patient ainsi que sur le plan du coût.

Mots-clés

cancer colorectal dépistage nouvelles technologies 

Screening for colorectal cancer in 2006

Summary

Colorectal cancer is the second leading cause of death in Northern countries and needs a national screening program to reduce mortality and improve quality of life.

Screening has to be cost-effective and acceptable for patients. Many screening tools, invasive or not, are existing and often debated: FOBT, sigmoidoscopy and complete colonoscopy.

New tools are in development and have to be evaluated in current practice: virtual colonoscopy, new endoscopic technologies, DNA on faeces or proteomics with markers in serum.

Key-words

colorectal cancer screening novel technologies 

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Références

  1. 1.
    Hakama M, Hoff G, Kronborg O, Pahlman L. Screening for colorectal cancer. Acta Oncol 2005; 44: 425–39.PubMedCrossRefGoogle Scholar
  2. 2.
    Ko C, Sonnenberg A. Comparing risks and benefits of colorectal cancer screening in elderly patients. Gastroenterol 2005; 129: 1163–70.CrossRefGoogle Scholar
  3. 3.
    Ochsenkuhn T, Bayerdorffer E, Meining A, Spath L, Mannes G, Wiebecke B, Eiermann W, Sackmann M, Goke B. Increased prevalence of colorectal adenomas in women with breast cancer. Digestion 2005; 72: 150–5.PubMedCrossRefGoogle Scholar
  4. 4.
    Tejpar S. Risk stratification for colorectal cancer and implications for screening. Acta Gastroenterolol Belg 2005; 68: 241–52.Google Scholar
  5. 5.
    Carter M, Lobo A, Travis S. Guidelines for the management of inflammatory bowel diseases in adults. Gut 2004; 53: V1-V16.PubMedCrossRefGoogle Scholar
  6. 6.
    Itzkowitz S, Present D. Consensus conference: colorectal cancer screening and surveillance in inflammatory bowel disease. Inflamm Bowel Dis 2005; 11: 314–21.PubMedCrossRefGoogle Scholar
  7. 7.
    Matano Y, Okada T, Suzuki A, Yoneda T, Takeda Y, Mabuchi H. Risk of colorectal neoplasm in patients with acromegaly ans its relationship with serum growth hormone levels. Am J Gastroenterol 2005; 100: 1154–60.PubMedCrossRefGoogle Scholar
  8. 8.
    Faivre J. Screening for colorectal cancer with faecal-occult-blood tests: trial evidence and beyond. Acta Gastroenterol Belg 2005; 68: 243–44.Google Scholar
  9. 9.
    Hardcastle JD, Chamberlain JO, Robinson MH, Moss SM, Amar SS, Balfour TW. Randomised controlled trial of faecal-occult-blood screening for colorectal cancer. Lancet 1996; 348: 1472–7.PubMedCrossRefGoogle Scholar
  10. 10.
    Kronborg O, Fenger C, Olsen J, Jorgensen OD, Sondergaard O. Randomised study of screening for colorectal cancer with faecal-occult-blood test. Lancet 1996; 348: 1467–71.PubMedCrossRefGoogle Scholar
  11. 11.
    Faivre J, Dancourt V, Lejeune C, Tori MA, Lamour J, Gerard D. Reduction in colorectal cancer mortality by fecal occult blood screening in a French control study. Gastroenterology 2004; 126: 1674–80.PubMedCrossRefGoogle Scholar
  12. 12.
    Janssens JF. Faecal-occult-blood test as a screening test for colorectal cancer. Acta Gastroenterol Belg 2005; 68: 244–46.PubMedGoogle Scholar
  13. 13.
    Janssens JF. Flexible sigmoidoscopy as a screening test for colorectal cancer. Acta Gastroenterol belg 2005; 68: 248–9.PubMedGoogle Scholar
  14. 14.
    Pabby A, Suneja A, Heeren T, Farraye FA. Flexible sigmoidoscopy for colorectal cancer screening in the elderly. Dig Dis Sci 2005; 50: 2147–52.PubMedCrossRefGoogle Scholar
  15. 15.
    Schoenfeld P, Cask B, Flood A, Dobhan R, Eastone J, Coyle W, Kikendall JW, Kim HM, Weiss DG, Emory T, Schatzkin A, Lieberma D. Colonoscopic screening of average-risk women for colorectal neoplasia. N Engl J Med 2005; 352: 2061–68.PubMedCrossRefGoogle Scholar
  16. 16.
    Binder H. Colonoscopy is superior to flexible sigmoidoscopy for colorectal cancer screening: now beyond a reasonable doubt? Gastroenterology 2005; 129: 1793–1800.CrossRefGoogle Scholar
  17. 17.
    Burke C, Elder K, Lopez R. Screening colorectal cancer with flexible sigmoidoscopy: is a 5 year interval appropriate? A comparison of the detection of neoplasia 3 yr versus 5 yr after a normal examination. Am J Gastroenterol 2006; 101: 1329–32.PubMedCrossRefGoogle Scholar
  18. 18.
    Schapira M, Adler M. Colonoscopy as a screening test for colorectal cancer. Acta Gastroenterol Belg 2005; 68: 251–6.PubMedGoogle Scholar
  19. 19.
    Nicholson F, Barro J, Bartram C, Dehmeshki J, Halligan S, Taylor S, Kamm M. The role of CT colonography in colorectal cancer screening. Am J Gastroenterol 2005; 100: 2315–23.PubMedCrossRefGoogle Scholar
  20. 20.
    Heitman S, Manns B, Hildsen R, Fong A, Dean S, Romagnuolo J. Cost effectiveness of computerized tomographic colonography versus colonoscopy for colorectal cancer screening. CMAJ 2005; 173: 877–81.PubMedGoogle Scholar
  21. 21.
    Macari M, Bini E. CT Colonography: where have we been and where are we going? Radiology 2005; 237: 819–33.PubMedCrossRefGoogle Scholar
  22. 22.
    Op De Beeck B, Van Cutsem E. Computed tomographic colonography. Acta Gastroenterol Belg 2005; 68: 258–60.PubMedGoogle Scholar
  23. 23.
    Summers R, Yao J, Pickhardt P, Franaszek M, Bitter I, Brickman D, Krishna V, Choi J. Computed tomographic virtual colonoscopy computed-aided polyp detection in a screening population. Gastroenterology 2005; 129: 1832–44.PubMedCrossRefGoogle Scholar
  24. 24.
    Shi R, Schraedley-Desmond P, Napel S, Olcott E, Jeffrey R, Yee J, Zalis M, Margolis D, Paik D, Sherbondy A, Sundaram P, Beaulieu C. CT colonography: influence of 3D viewing and polyp candidate features on interpretation with computer-aided-detection. Radiology 2006; 239: 768–76.PubMedCrossRefGoogle Scholar
  25. 25.
    Feldman A, Espina V, Petricoin E, Liotta L, Rosenblatt K. Use of proteomic patterns to screen for gastrointestinal malignancies. Surgery 2004; 135: 243–7.PubMedCrossRefGoogle Scholar
  26. 26.
    Regueiro C. AGA future trends committee report: colorectal cancer: a qualitative review of emerging screening and diagnostic technologies. Gastroenterology 2005; 129: 1083–1103.PubMedCrossRefGoogle Scholar
  27. 27.
    Osborn N, Ahlquist D. Stool screening for colorectal cancer: molecular approaches. Gastroenterology 2005; 128: 192–206.PubMedCrossRefGoogle Scholar
  28. 28.
    Hurlstone D, Karajeh M, Cross S, Mcalindon M, Brown S, Hunter M, Sanders D. The role of High-Magnification-Chromoscopic colonoscopy in hereditary nonpolyposis colorectal cancer screening: a prospective “back-to-back” endoscopic study. Am J Gastroenterol 2005; 100: 2167–73.PubMedCrossRefGoogle Scholar
  29. 29.
    Kiesslich R, Neurath M. Magnifying chromoendoscopy for the detection of premalignant gastrointestinal lesions. Best Pract Res Clin Gastroenterol 2006; 20: 59–78.PubMedCrossRefGoogle Scholar
  30. 30.
    Kiesslich R, Hoffman A, Neurath MF. Colonoscopy, tumors, and inflammatory bowel disease — new diagnostic methods. Endoscopy 2006; 38: 5–10.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Patricia Piront
    • 1
    • 2
  • E. Louis
    • 1
    • 2
  • J. Belaiche
    • 1
    • 2
  • M. Polus
    • 1
    • 2
  1. 1.service de gastroentérologieCHU de LiègeLiègeBelgique
  2. 2.CBIG-GIGA University of LiègeBelgium

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