Polynoxylin in the treatment of varicose ulcers
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82 consecutive female patients with 85 varicose ulcers were treated by compression sclerotherapy for varicose veins. The areas of the ulcers were measured by projecting scaled photographs of the ulcers on to squared paper and drawing the outline. It is shown that indirect methods of measuring areas of ulcers are unsatisfactory.
Alternate patients had their ulcers treated with a dressing of polynoxylin paste on sterile lint. Control patients had a dressing of sterile lint alone. In 17 pairs of treated and control patients, with ulcers matched for size, the rates of healing were 2.8 and 3.1 sq. mms. per day respectively. The difference is not statistically significant. Polynoxylin was not shown to influence the rate of epithelialisation of varicose ulcers.
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