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Polynoxylin in the treatment of varicose ulcers

  • J. M. Pegum
  • W. G. Fegan
Article

Summary

82 consecutive female patients with 85 varicose ulcers were treated by compression sclerotherapy for varicose veins. The areas of the ulcers were measured by projecting scaled photographs of the ulcers on to squared paper and drawing the outline. It is shown that indirect methods of measuring areas of ulcers are unsatisfactory.

Alternate patients had their ulcers treated with a dressing of polynoxylin paste on sterile lint. Control patients had a dressing of sterile lint alone. In 17 pairs of treated and control patients, with ulcers matched for size, the rates of healing were 2.8 and 3.1 sq. mms. per day respectively. The difference is not statistically significant. Polynoxylin was not shown to influence the rate of epithelialisation of varicose ulcers.

References

  1. Alexander, J. O’D. (1962). “Polynoxylin (Anaflex) in dermatology,”Brit. J. Derm., 74, 364.PubMedGoogle Scholar
  2. Fegan, W. G. (1967).Varicose Veins: their treatment by compression sclerotherapy. London: Heinemann.Google Scholar
  3. Fegan, W. G. and Pegum, J. M. (1966). “Venous leg ulcers,”Brit. Med. J., 2, 1391.PubMedCentralCrossRefGoogle Scholar
  4. Haeger, K. (1963). “Pre-operative treatment of leg ulcers with silver spray and aluminium foil,”Acta Chir. Scand., 125, 32.PubMedGoogle Scholar
  5. Haler, D. (1964). “Polynoxylin: a new antiseptic,”Brit. J. Clin. Practice, 18, 267.Google Scholar
  6. Haler, D. and Aebi, A. (1961). “A new highly effective but non-toxic antibacterial substance,”Nature, 190, 734.PubMedCrossRefGoogle Scholar
  7. Luger, A. (1952). “Heilungstendenz beim Ulcus cruris,”Der Hautarzt, 3, 360.Google Scholar

Copyright information

© Springer 1968

Authors and Affiliations

  • J. M. Pegum
  • W. G. Fegan

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