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Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine

  • Lianbo Wei
  • Rengao Ye
  • Xuhong Chen
  • Zhijun Li
  • Ruihe Lu
  • Tu Luan
Original Articles
  • 18 Downloads

Abstract

Objective: To observe the clinical effect of integrated traditional Chinese and western medicine (TCM-WM) in treating senile idiopathic nephrotic syndrome (SINS).Methods: Eighty-two patients of SINS were randomly divided into two groups. The 41 patients in the TCM-WM group were treated with prednisone, Cytoxan (CTX) and Chinese medicinal herbs according to Syndrome-type, and the 41 patients in the control group were treated with western medicine alone. The clinical remission rate and time, recurrence rate in patients as well as adverse reaction rate occurred were observed.Results: The complete remission rate and total effective rate of the TCM-WM group were 58.5% and 85.4 %, which were significantly higher than those of the control group (39.0% and 63.4 %,P < 0.01 ). The adverse reaction rate in the TCM-WM group was 36.6 %, which was significantly lower than that of the control group (80.5%, P<0.01). A follow-up of 35.1 ± 9. 7 months showed that there was no significant difference in the recurrence rate between the two groups (P > 0.05 ), but the average remission period (30.6 ± 3.8 months) of the TCM-WM group was significantly longer than that of the control group (12.7±3.7 months, P<0.01).Conclusion: TCM-WM treatment is obviously superior to that with western medicine alone in increasing clinical remission rate, relieving adverse reaction rate and extending remission period.

Key Words

integrated traditional Chinese and western medicine senility idiopathic nephrotic syndrome 

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References

  1. 1.
    Deng TT, edit. Norm of TCM Syndromes. Guangzhou: Guangdong Press of Science and Technology, 1990:244.Google Scholar
  2. 2.
    Ye RG. Current progression of treatment of nephrotic syndrome. New Chinese Medicine 1990;21(8):428.Google Scholar
  3. 3.
    Zeng CH, Chen HP, Li LS. Epidemiologic and pathologic type analysis of senile nephropathy. Chin J Nephrology, Dialysis and Transplantation 1997;6(5):411.Google Scholar
  4. 4.
    Glassock RJ, Adler SG, Ward HJ, et al. Primary glomeruler diseases; In: Brenner BM, ed. The Kidney. 5th Edition. Laldelphia Sannders, 1996:1212–1297.Google Scholar
  5. 5.
    Chen SH, Ye RG, Li HQ. Clinical observation on treatment of nephritis nephrotic syndrome by integrated traditional Chinese and western medicine. Chin J Nephrology 1995;11(6):357.Google Scholar
  6. 6.
    Li LS, Tai WS. Observation on prevention and treatment of 135 cases of iatrogenic Cushing ’ s syndrome by Liuwei Dihuang Pill. Practical J Integrated Chinese with Modern Medicine 1995;8(9):525.Google Scholar

Copyright information

© The Chinese Journal of Integrated Traditional and Western Medicine Press 2000

Authors and Affiliations

  • Lianbo Wei
    • 1
  • Rengao Ye
    • 2
  • Xuhong Chen
    • 3
  • Zhijun Li
    • 1
  • Ruihe Lu
    • 1
  • Tu Luan
    • 3
  1. 1.Department of TCM Internal Medicine, Nanfang HospitalFirst Military Medical UniversityGuangzhou
  2. 2.Institute of NephropathySun Yat-sen Medical UniversityChina
  3. 3.Training Center of Guangdong Provincial Federation of DeformityChina

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