Spontaneous regression of metastatic renal cell carcinoma following palliative irradiation of the primary tumour
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A 58 years old man presented with a bulky renal primary tumour, paratracheallymphadenopathy and multiple pulmonary metastases. Spontaneous regression of intrathoracic metastases occurred after low dose palliative irradiation of the primary tumour. Serum levels of Interleukin-2 receptor were elevated during the period of tumour regression but concentrations of other cytokines were normal. Progressive abdominal disease eventually caused death. Autopsy confirmed the presence of renal cell carcinoma with intrathoracic metastases.
KeywordsRenal Cell Carcinoma Metastatic Renal Cell Carcinoma Renal Carcinoma Spontaneous Regression Palliative Irradiation
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- 1.Everson, T. C., Cole, W. M. Spontaneous Regression of Cancer. Philadelphia: W.B. Saunders, 1966: 11–87.Google Scholar
- 4.Muss, H. B. Renal cell carcinoma. In: DeVita, V. T., Hellman, S., Rosenberg, S. A. eds. Biologic therapy of cancer. Philadelphia: J. B. Lippincott Co., 1991: 298–311.Google Scholar
- 11.Pansera, F. Regression in renal cell carcinoma as re-expression of cell death in kidney development. Perspectives in Biology & Medicine 1992: 426–21.Google Scholar
- 16.Cotran, R. S., Kumar, V., Robbins, S. I. Robbins. Pathologic Basis of Disease, 4th ed. Philadelphia: W. B. Saunders; 1989: 686.Google Scholar