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Mycotoxin Research

, Volume 19, Issue 1, pp 82–86 | Cite as

Trichothecene resistance in wheat: Development of molecular markers for PDR-type ABC transporter genes

  • R. Mitterbauer
  • M. Heinrich
  • R. Rauscher
  • M. Lemmens
  • H. Bürstmayr
  • G. Adam
Article

Abstract

Infection withFusarium graminearum andF. culmorum not only causes severe yield and quality losses, the most relevant concern is the contamination of cereal foods and feeds with trichothecenes (e.g. deoxynivalenol, DON). The ability to synthesize trichothecenes has been shown to be a virulence factor ofF. graminearum on wheat and, on the other hand, toxin resistance is most likely an important component of field resistance. Our hypothesis is that pleiotropic drug resistance mediated by PDR-type ABC transporter proteins (acting as membrane located drug efflux pumps) is a relevant mechanism of DON resistance not only in yeast but also in wheat. Goal of this project is the development of molecular markers for this gene family for use in marker-assisted plant breeding programs. The technical difficulties caused by the large size of the PDR-family are discussed.

Keywords

Fusarium deoxynivalenol PDR marker 

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Copyright information

© Society of Mycotoxin Research and Springer 2003

Authors and Affiliations

  • R. Mitterbauer
    • 1
  • M. Heinrich
    • 1
  • R. Rauscher
    • 1
  • M. Lemmens
    • 2
  • H. Bürstmayr
    • 2
  • G. Adam
    • 1
  1. 1.Center of Applied GeneticsBOKU - University of Natural Resources and Applied Life SciencesViennaAustria
  2. 2.Department of Plant Production BiotechnologyInstitute for Agrobiotechnology TullnTullnAustria

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