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Irish Journal of Medical Science

, Volume 150, Issue 1, pp 210–212 | Cite as

The value of a second oral lactose tolerance test in detecting hypolactasia

  • J. F. Fielding
Article

Summary

Asecond oral lactose tolerance test is a useful discriminatory test for intestinal lactase activity. When the maximum blood glucose rise changes between tests by more than 1.0 mmol/litre intestinal lactase activity is almost certainly normal; if the maximm rise is initially low and changes by less than 0.5 mmol/litre on repeat testing it is highly probable that intestinal lactase activity is low. Subjective stress may play a role in false low oral lactose tolerance tests.

Keywords

Irritable Bowel Syndrome Lactase Subjective Stress Maximum Rise Lactase Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Dahlqvist, A. 1968. Assay of intestinal disaccharidases. Analytical Biochemistry 22, 99–107.PubMedCrossRefGoogle Scholar
  2. Fielding, J. F. 1980. The half-hour lactose “tolerance” test in adults. Jour. Irish. Med. Ass. 73, 21–22.Google Scholar
  3. Johnson, J. D., Simoons, F. J., Hurwitz, Ruth, Grange, A., Mitchell, C. H., Sinatra, F. R., Sunshine, P., Robertons, W. V., Bennett, P. H. and Kretchmer, N. 1977. Lactose malabsorption amongst the Pima Indians of Arizona. Gastroenterology 73, 1299–1304.PubMedGoogle Scholar
  4. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. 1951. Protein measurement with the Folin phenol reagent. Jour. of Biological Chemistry 193, 265–275.Google Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • J. F. Fielding
    • 1
  1. 1.Department of Medicine and GastroenterologyThe Charitable InfirmaryDublin 1

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