Herpes simplex encephalitis and sarcoidosis

  • E. C. Sweeney
  • L. McDonnell
Brief Report


Fatal herpes simplex encephalitis occurring in a patient with sarcoidosis is described. Ultrastructural study of brain tissue revealed the presence of herpesvirus particles. The association of these 2 diseases has not been recorded before. The encephalitis in this case probably represents an opportunistic viral infection in the face of depressed cellular immunity. Progressive multifocal leukoencephalopathy, a disease of putative viral aetiology, is known to occur in patients with sarcoidosis and it is suggested that this case represents a similar pathogenetic association.


Herpes Simplex Encephalitis Sarcoidosis Progressive Multifocal Leukoencephalopathy Herpes Simplex Encephalitis 
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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • E. C. Sweeney
    • 1
  • L. McDonnell
    • 1
  1. 1.School of PathologyTrinity CollegeDublin

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