Secretory IgA in saliva can be a useful stress marker

  • Satoshi Tsujita
  • Kanehisa Morimoto


To evaluate secretory immunoglobulin A (slgA) in saliva as an immunological stress marker, we reviewed the literature on slgA and its variation caused by psychosocial factors. Among the studies on the effect of academic stress on slgA secretion, we could distinguish two kinds of stress effects: the immediate stress effect which increases slgA secretion immediately after stress, and the delayed stress effect which decreases slgA secretion several days after stress. On the basis of production and secretion mechanisms of slgA, we also speculated on possible mechanisms that underlie the variations of slgA caused by stress. Eventually, we concluded diat slgA in saliva can be a useful stress marker if we analyze the delayed stress effect on slgA separately from the immediate stress effect on slgA.

Key words

IgA secretory marker stress saliva 


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Copyright information

© Japanese Society of Hygiene 1999

Authors and Affiliations

  • Satoshi Tsujita
    • 1
  • Kanehisa Morimoto
    • 1
  1. 1.Department of Hygiene and Preventive MedicineOsaka University School of MedicineOsakaJapan

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