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Folia Microbiologica

, Volume 30, Issue 4, pp 373–380 | Cite as

The effect of bilirubin on the fc receptor expression and phagocytic activity of mouse peritoneal macrophages

  • V. Větvička
  • I. Miler
  • P. Šíma
  • L. Táborský
  • L. Fornůsbk
Article

Abstract

The effect of bilirubin on the phagocytic activity of mouse peritoneal macrophages and on the expression of Fc receptors and receptors for SRBC was studied. Intraperitoneally administered bilirubin influenced the expression of Fc receptors for IgM, IgG2B, IgA and IgE, whereas the expression of other receptors as well as the phagocytic activity of peritoneal macrophages remained unchanged. The possible mechanism of the effect of bilirubin on Fc receptors is discussed.

Keywords

Bilirubin Peritoneal Macrophage Phagocytic Activity Mouse Peritoneal Macrophage Peritoneal Macro 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

ADCC

antibody-dependent cell cytotoxicity

FcR

receptor for the Fc fragment of an immunoglobulin

PBS

phosphate-buffered saline

PHA

phytohemagglutinin

SRBC

sheep red blood cells

TNP

2,4,6-trinitrophenyl

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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1985

Authors and Affiliations

  • V. Větvička
    • 1
  • I. Miler
    • 1
  • P. Šíma
    • 1
  • L. Táborský
    • 1
  • L. Fornůsbk
    • 1
  1. 1.Institute of MicrobiologyCzechoslovak Academy of SciencesPrague 4

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