Incorporation of tellurium into amino acids and proteins in a tellurium-tolerant fungi

  • Shadia E. Ramadan
  • A. A. Razak
  • A. M. Ragab
  • M. El-Meleigy


Aspergillus fumigatus, Aspergillus terreus, andPenicillium chrysogenum, a tellurium tolerant fungi, are able to grow on sulfur free medium amended with 0.2% (w/v) tellurite. Tellurium was incorporated into several types of low and high molecular weight proteins. The newly detected telluro-proteins contained an extraordinary high level of tellurium, as well as telluro-cysteine, telluro-cystine, telluro-methionine, and serine.

Index Entries

Tellurium-tolerant fungi telluro-amino acids telluro-cysteine telluro-cystine telluro-methionine telluro-protein 


  1. 1.
    R. P. Beliles, inToxicity of Heavy. Metals in the Environment, part 2, F. W. Oehme, ed., Dekker, New York and Basel, 1979, pp. 547–615.Google Scholar
  2. 2.
    F. L. Tucker, J. F. Walper, Milo Don Appleman, and D. Jerry,J. Bacteriol. 83, 1313 (1962).PubMedGoogle Scholar
  3. 3.
    S. Nagai,J. Bacteriol. 90(1), 220 (1965).PubMedGoogle Scholar
  4. 4.
    D. G. Smith,J. Gen. Microbiol. 83, 389 (1974).PubMedGoogle Scholar
  5. 5.
    H. E. Morton and T. F. Anderson,Proc. Soc. Exp. Biol. Med. 46, 272–276 (1941).Google Scholar
  6. 6.
    H. L. David, N. Rastogi, C. Frehel, and M. Gheorghiu,Ann. Microbiol. 133(1), 129 (1982).Google Scholar
  7. 7.
    S. E. Ramadan, B. M. Haroun, and A. A. Razak,Proc. Egypt Soc. Appl. Microbiol. p. 159 (1983).Google Scholar
  8. 8.
    D. Siliprandi, R. H. De Meio, A. Toninello, and F. Zoccarato,Biochem. Biophys. Res. Commun. 45, 1071 (1971).PubMedCrossRefGoogle Scholar
  9. 9.
    R. L. Bieleski and N. A. Turner,Anal. Biochem. 17, 278 (1966).PubMedCrossRefGoogle Scholar
  10. 10.
    R. S. Ersser and I. Smith, inChromatographic and Electrophoretic Techniques, V.I: Paper and Thin Layer Chromatography, I. Smith and J. W. T. Seakins, eds., Heinemann, 1976, pp. 75–108.Google Scholar
  11. 11.
    W. Nielsch and L. Z. Giefer,Anal. Chem. 155, 401 (1957).CrossRefGoogle Scholar
  12. 12.
    B. J. Davis,Ann. NY Acad. Sci. 121, 404 (1964).PubMedCrossRefGoogle Scholar
  13. 13.
    O. H. Lowry, N. J. Rosebrough, A. L. Farr, and R. J. Randall,J. Biol. Chem. 193, 265 (1951).PubMedGoogle Scholar
  14. 14.
    K. Lerch, inMetallothionein, J. H. R. Kägi and M. Nordberg, eds., Birkhäuser, Basle, 1979, pp. 173–179.Google Scholar
  15. 15.
    J. H. R. Kägi and B. L. Vallee,J. Biol. Chem. 235, 3460 (1960).PubMedGoogle Scholar
  16. 16.
    M. O. Dayhoff,Atlas of Protein Sequence and Structure, vol. 5, supplement 3, Natl. Biomed. Res. Found., Washington, DC, 1978.Google Scholar
  17. 17.
    T. A. Brown, Ph.D. thesis, University of London, London (1978).Google Scholar
  18. 18.
    J. A. Fee,Struct. Bond. 23, 1 (1975).CrossRefGoogle Scholar
  19. 19.
    M. Nordberg and Y. Kojima, inMetallothionein, J. H. R. Kägi and M. Nordberg, eds., Birkhäuser, Basle, 1979, pp. 41–124.Google Scholar

Copyright information

© The Humana Press Inc. 1989

Authors and Affiliations

  • Shadia E. Ramadan
    • 1
  • A. A. Razak
    • 1
  • A. M. Ragab
    • 1
  • M. El-Meleigy
    • 1
  1. 1.Department of Botany, Faculty of ScienceAl-Azhar UniversityCairoEgypt

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