Biological Trace Element Research

, Volume 41, Issue 1–2, pp 129–135

Determination of aluminum levels in the kidney, liver, and brain of mice treated with aluminum hydroxide

  • Gönül Şahin
  • I. Varol
  • A. Temizer
  • K. Benli
  • R. Demirdamar
  • S. Duru
Article
  • 60 Downloads

Abstract

In the present study, aluminum (Al) accumulation has been examined after aluminum loading in mice. The kidney, liver, and brain aluminum levels for mice that had been treated orally with aluminum hydroxide for 105 d and for the control group were determined using graphite furnace atomic absorption spectrophotometry (GFAAS) following an acid digestion. Matrix modifier consisted of 2% Triton X-100 and 2% Mg (NO3)2.

Al loaded mice showed a significant increase in tissue aluminum levels, relative to the control group.

Index Entries

Accumulation of aluminum graphite furnace atomic absorption acid digestion bomb matrix modifier 

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Copyright information

© Humana Press Inc. 1994

Authors and Affiliations

  • Gönül Şahin
    • 1
  • I. Varol
    • 2
  • A. Temizer
    • 2
  • K. Benli
    • 3
  • R. Demirdamar
    • 4
  • S. Duru
    • 1
  1. 1.Department of Pharm. ToxicologyHacettepe UniversityAnkaraTurkey
  2. 2.Department of Analytical ChemistryHacettepe UniversityAnkaraTurkey
  3. 3.Department of NeurosurgeryHacettepe UniversityAnkaraTurkey
  4. 4.Department of PharmacologyHacettepe UniversityAnkaraTurkey

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