Annals of Behavioral Medicine

, Volume 21, Issue 2, pp 180–191 | Cite as

A meta-analysis of fibromyalgia treatment interventions

  • Lynn A. Rossy
  • Susan P. Buckelew
  • Nancy Dorr
  • Kristofer J. Hagglund
  • Julian F. Thayer
  • Matthew J. McIntosh
  • John E. Hewett
  • Jane C. Johnson
Literature Review and Meta-Analysis

Abstract

Objective: To evaluate and compare the efficacy of pharmacological and nonpharmacological treatments of fibromyalgia syndrome (FMS). Methods: This meta-analysis of 49 fibromyalgia treatment outcome studies assessed the efficacy of pharmacological and nonpharmacological treatment across four types of outcome measures—physical status, self-report of FMS symptoms, psychological status, and daily functioning. Results: After controlling for study design, antidepressants resulted in improvements on physical status and self-report of FMS symptoms. All nonpharmacological treatments were associated with significant improvements in all four categories of outcome measures with the exception that physically-based treatment (primarily exercise) did not significantly improve daily functioning. When compared, nonpharmacological treatment appears to be more efficacious in improving self-report of FMS symptoms than pharmacological treatment alone. A similar trend was suggested for functional measures. Conclusion: The optimal intervention for FMS would include nonpharmacological treatments, specifically exercise and cognitive-behavioral therapy, in addition to appropriate medication management as needed for sleep and pain symptoms.

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Copyright information

© The Society of Behavioral Medicine 1999

Authors and Affiliations

  • Lynn A. Rossy
    • 1
  • Susan P. Buckelew
    • 1
  • Nancy Dorr
    • 2
  • Kristofer J. Hagglund
    • 1
  • Julian F. Thayer
    • 1
  • Matthew J. McIntosh
    • 1
  • John E. Hewett
    • 1
  • Jane C. Johnson
    • 1
  1. 1.Department of PsychologyUniversity of MissouriColumbiaUSA
  2. 2.Jamestown CollegeJamestownUSA

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