Spontaneous abortion in spouses of greenhouse workers exposed to pesticides

  • Grazia Petrelli
  • Irene Figà-Talamanca
  • Laura Lauria
  • Alberto Mantovani
Original Article

Abstract

Objective

The aim of this study was to explore the association between exposure to specific pesticides (including endocrine disrupters) of greenhouse workers and spontaneous abortion in their spouses.

Methods

A group of exposed workers was compared with a non-exposed group. The risk of spontaneous abortion was evaluated using a logistic regression model.

Results

A significantly higher rate of spontaneous abortion was observed among spouses of workers exposed to specific compounds (atrazine, benomyl-carbendazim, carbaryl and DDT) in comparison with spouses of the unexposed group. The logistic regression model confirmed the increased risk of spontaneous abortion (OR=11.8; 95% CI 2.3–59.6).

Conclusions

These findings suggest that occupational exposure to pesticides might have an adverse effect on the partner’s reproductive health.

Key words

reproduction endocrine disrupters pregnancy loss epidemiology paternal exposure 

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Copyright information

© Japanese Society of Hygiene 2003

Authors and Affiliations

  • Grazia Petrelli
    • 1
  • Irene Figà-Talamanca
    • 2
  • Laura Lauria
    • 1
  • Alberto Mantovani
    • 3
  1. 1.Laboratorio di Epidemiologia e BiostatisticaIstituto Superiore di SanitàRomeItaly
  2. 2.Dipartimento di Biologia Animale e dell’UomoUniversità “La Sapienza”RomeItaly
  3. 3.Laboratorio di Tossicologia Comparata ed EcotossicologiaIstituto Superiore di SanitàRomeItaly

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