Indian Journal of Clinical Biochemistry

, Volume 20, Issue 1, pp 85–86 | Cite as

Effect of vitamin A supplementation on hematopoiesis in children with anemia

  • Arun Garg
  • Pankaj Abrol
  • AD Tewari
  • Rajiv Sen
  • Harbans Lal


Fifty children (1–4 years age) presenting with microcytic hypochromic anemia (hemoglobin less than 10g/dl) were studied in two groups of 25 each. Group I was supplemented with iron (ferrous sulphate 6 mg/kg/d) while group II in addition to iron was also supplemented with vitamin A (5000 IU/d). Hemoglobin concentration was found to be significantly increased after 4 weeks of iron supplementation. Rise in hemoglobin was comparatively more in-group II, as compared to group I, after 8 and 12 weeks. Serum iron was significantly higher after 4 weeks in both the groups. Packed cell volume (PCV) and retinol levels increased significantly in-group II only. The data suggests that supplementation of vitamin A improves hematopoiesis.

Key Words

Vitamin A Hematopoiesis Anemia 


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Copyright information

© Association of Clinical Biochemists of India 2005

Authors and Affiliations

  • Arun Garg
    • 1
  • Pankaj Abrol
    • 1
  • AD Tewari
    • 1
  • Rajiv Sen
    • 2
  • Harbans Lal
    • 3
  1. 1.Departments of PediatricsPt. BD Sharma Post Graduate Institute of Medical SciencesRohtak(Haryana)
  2. 2.PathologyPt. BD Sharma Post Graduate Institute of Medical SciencesRohtak(Haryana)
  3. 3.BiochemistryPt. BD Sharma Post Graduate Institute of Medical SceincesRohtak(Haryana)

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