Virchows Archiv B

, 52:375 | Cite as

Renal oncocytoma: origin from the collecting duct

  • Heide Zerban
  • Enrique Nogueira
  • Gerd Riedasch
  • Peter Bannasch


The histo- and cytogenesis of two cases of renal oncocytoma have been studied by cytomorphological and cytochemical methods. Transitions from collecting ducts into oncocytic tubules were observed at the light and electron microscopic levels. The fine structure of the oncocytes in tubules and tumors is described in detail. Cytochemically, the oncocytic tubules and oncocytomas share many characteristics with the distal nephron, especially the collecting ducts. A striking difference is the enhanced activity of succinic dehydrogenase which corresponds to the increase in the number of mitochondria in oncocytes. All the results suggest that renal oncocytoma originates from the collecting duct.

Key words

Renal oncocytoma Oncocytic tubules Collecting duct 


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Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • Heide Zerban
    • 1
  • Enrique Nogueira
    • 1
  • Gerd Riedasch
    • 2
  • Peter Bannasch
    • 1
  1. 1.Institut für Experimentelle PathologieDeutsches KrebsforschungszentrumHeidelberg
  2. 2.Urologische AbteilungChirurgische Universitätsklinik HeidelbergHeidelbergFederal Republic of Germany

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