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Folia Microbiologica

, 28:397 | Cite as

Determination of optimum conditions for antibiotic production byStreptomyces galbus

  • A. K. Paul
  • A. K. Banerjee
Article

Abstract

The nutritional requirements and cultural conditions for optimal production of a new extracellular antifungal antibiotic byStreptomyces galbus under laboratory conditions were determined. Glycerol and glucose were found to be the best carbon sources, while as N-source nitrate was preferred. Maximum titre was reached after 7 d of incubation at 30 °C at pH 6.8. The metal ions Cu2+, Zn2+, Mn2+ and Fe2+ had some promoting effect. Casein hydrolysate improved production, but yeast extract markedly inhibited. Growth in shake flasks favoured higher yield of the antibiotic in a shorter time.

Keywords

Streptomyces Casein Hydrolysate Antibiotic Production Organic Nitrogen Source Antifungal Antibiotic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1983

Authors and Affiliations

  • A. K. Paul
    • 1
  • A. K. Banerjee
    • 1
  1. 1.Microbiology Laboratory, Department of BotanyBurdwan UniversityBurdwan 713 104, West BengalIndia

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