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Folia Microbiologica

, Volume 32, Issue 4, pp 345–348 | Cite as

The dsRNA ofTrichomonas vaginalis is associated with virus-like particles and does not correlate with metornidazole resistance

  • J. Flegr
  • J. Čerkasov
  • J. Kulda
  • J. Tachezy
  • J. Štokrová
Article

Abstract

Twelve metronidazole-resistant and twelve metronidazole-susceptible strains ofTrichomonas vaginalis were tested for the presence of dsRNA. Three resistant and five susceptible strains were found to contain dsRNA which indicated that metronidazole resistance does not correlate with the absence of dsRNA. Electron microscopy showed the homogenates of all dsRNA -positive strains to contain virus-like particles 32 –38 nm in diameter, while no such particles were found in the dsRNA-negative strains. A mutual relationship between the dsRNA and virus-like particles seems to exist.

Keywords

Metronidazole Susceptible Strain Positive Strain Entamoeba Histolytica Trichomoniasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1987

Authors and Affiliations

  • J. Flegr
    • 1
  • J. Čerkasov
    • 1
  • J. Kulda
    • 1
  • J. Tachezy
    • 1
  • J. Štokrová
    • 2
  1. 1.Faculty of ScienceCharles UniversityPrague 2
  2. 2.Institute of Molecular GeneticsCzechoslovak Academy of SciencesPrague 6

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