Folia Microbiologica

, Volume 22, Issue 1, pp 55–60 | Cite as

Growth, glucose metabolism and melanin formation in biotin-deficientAspergillus nidulans

  • J. D. Desai
  • V. V. Modi
Article
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Abstract

Biotin deficiently resulted in an increased growth rate ofAspergillus nidulans. The activities of hexokinase and aldolase were not much changed during the growth cycle, but activities of glucose-6-phosphate dehydrogenase and NADP-linked glutamate dehydrogenase increased significantly during the exponential phase. This change was remarkable during biotin deficiency. In contrast to the higher growth rate and respiration rate during biotin deficiency the activities of NAD(P)H oxidoreductases were low. An inverse relationship between the activity of tyrosinase and melanin content was observed. A role of the DOPA-DOPA-quinone system in maintaining culture growth is suggested.

Keywords

Dopa Aldolase Glutamate Dehydrogenase Melanin Content Melanin Formation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1977

Authors and Affiliations

  • J. D. Desai
    • 1
  • V. V. Modi
    • 1
  1. 1.Department of Microbiology, Faculty of ScienceM.S. University of BarodaBarodaIndia

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