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Indian Journal of Clinical Biochemistry

, Volume 4, Issue 1, pp 62–64 | Cite as

Hyperlipidemia in guinea pigs induced by chronic vitamin C deficiency

  • Praveen Sharma
  • P. K. Sharma
  • J. Pramod
  • L. K. Kothari
  • Rashmi Ranka
  • Sushma Sharma
Article

Abstract

Sixteen weeks of chronic vitamin C deficiency, induced in guinea pigs by restricted vitamin C intake, resulted in a marked increase in the serum total LDL- and VLDL- cholesterol, triglycerides and total lipids. HDL-cholesterol decreased resulting in a highly significant increase in LDL/HDL ratio. The results reconfirm that vitamin C deficiency causes changes in blood lipid profile which could promote atherogenesis.

Keywords

Total Lipid Deficient Diet Blood Lipid Profile Scurvy Lower Blood Cholesterol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Association of Clinical Biochemists of India 1989

Authors and Affiliations

  • Praveen Sharma
    • 1
    • 2
  • P. K. Sharma
    • 1
    • 2
  • J. Pramod
    • 1
    • 2
  • L. K. Kothari
    • 1
    • 2
  • Rashmi Ranka
    • 1
    • 2
  • Sushma Sharma
    • 1
    • 2
  1. 1.Department of BiochemistryDr. S.N. Medical CollegeJodhpur
  2. 2.Department of BiochemistryJ.L.N. Medical CollegeAjmer

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