Indian Journal of Clinical Biochemistry

, Volume 4, Issue 1, pp 50–57 | Cite as

Changes in serum lipids in normal and diabetic guinea pigs on feeding Phaseolus aureus (Green gram)

  • Anurag Srivastava
  • L. D. Joshi
  • S. P. Singh


Normal and alloxan induced diabetic guinea pigs were kept on whole seed diet of green gram for 4 weeks. Serum total lipids were found to be significantly decreased in both normal and diabetic guinea pigs (P <0.001)—Both free and esterified fractions of cholesterol were found to be lowered significantly in diabetic animals (P<0.05; <0.01, respectively), whereas only esterified fraction was reduced significantly in case of normals (P<0.05). Significant lowering of triglyceride levels (P<0.01) was also noticed in both normal as well as diabetic guinea pigs while phospholipids remained almost unaffected. Green gram feeding decreased the total cholesterol / phospholipid ratio from 0.630 to 0.625 in normal and from 1.039 to 0.850 in diabetic guinea pigs indicating its antiatherogenic nature.


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Copyright information

© Association of Clinical Biochemists of India 1989

Authors and Affiliations

  • Anurag Srivastava
    • 1
  • L. D. Joshi
    • 1
  • S. P. Singh
    • 1
  1. 1.Department of BiochemistryM.L.B. Medical CollegeJhansiIndia

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