Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer
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Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.
Key words5′-NT ADA CA-125 Ovarian cancer
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- 6.Geeta Rathnakumar and Raste, A.S. (2000) Can 5′-Nucleotidase estimation be a predictor of liver metastasis? Ind. J. Cancer 37, 23–27.Google Scholar
- 7.Giusti, G. (1974) Adenosine deaminase. In: Methods of Enzymatic Analysis. Ed: Bergmeyer, H.U. Academic Press Inc., New York 20, 204–229.Google Scholar
- 8.Raymond, John Wood and David, Gwynne Williams (1981) Colorimetric determination of serum 5′-NT without deproteinization. Clin. Chem. 27 (3), 464–465.Google Scholar