Sedative activity and its active components of Zizyphi fructus

  • Byung Hoon Han
  • Myung Hwan Park


Sedative activity of Zizyphi fructus was evaluated by potentiation of hexobarbital-induced hypnosis test and its active principles have been characterized as nornuciferine and lysicamine. A new cyclopeptide alkaloid, daechucyclopeptide-1 was isolated together with zizyphusine.


Zizyphi fructus Zizyphus jujuba var.inermis Rhamnaceae sedative active principles nornuciferine lysicamine zizyphusine cyclopeptide alkaloid daechucyclopeptide-1 

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Copyright information

© The Pharmaceutical Society of Korea 1987

Authors and Affiliations

  • Byung Hoon Han
    • 1
  • Myung Hwan Park
    • 1
  1. 1.Natural Products Research InstituteSeoul National UniversitySeoulKorea

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