Archives of Pharmacal Research

, Volume 13, Issue 3, pp 215–220 | Cite as

First derivative spectrophotometric and gas-liquid chromatographic determination of caffeine in foods and pharmaceuticals III. Simultaneous assay of caffeine and some antihistaminics

  • Ezzat M. Abdel-Moety
  • Mohamed F. El-Tarras
  • Badr-Eldin A. El-Zeany
  • Khadiga O. Kelani
Original Articles


Two different, derivative spectrophotometric and gas-liquid chromatographic, procedures for direct quantitation of caffeine and some commonly dispensed antihistaminics in bulk forms, in their laboratory prepared mixtures and in dosage formulations, have been investigated. The limit, sensitivity, reproducibility and accuracy of each method were studied for each individual drug substance and in some usual pharmaceutical formulations.


Caffeine antihistamine first derivative spectrophotometric determination gas-liquid chromatographic determination 


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Copyright information

© The Pharmaceutical Society of Korea 1990

Authors and Affiliations

  • Ezzat M. Abdel-Moety
    • 1
  • Mohamed F. El-Tarras
    • 1
  • Badr-Eldin A. El-Zeany
    • 1
  • Khadiga O. Kelani
    • 1
  1. 1.Department of Analytical Chemistry, Faculty of PharmacyCairo UnivesityCairoEgypt

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