One-pot, three-component, sequential Michael-Michael-ring-closure reactions. Annulation of meta-dicarboxylated aromatic rings. Total synthesis of juncunol

  • Gary H. Posner
  • Karen A. Canella
  • Ernest F. Silversmith
Special Issue on Organic Synthesis

Abstract

The preparative value of one-pot, multicomponent, sequential Michael-Michael-ring-closure reactions followed by aromatization is illustrated in two ways: (1) by a multi-gram example, and (2) by a total synthesis of juncunol, an unusual vinyldihydrophenanthrene.

Keywords

Sequential Michael-Michael-ring-closure reactions one-pot reactions benzannulations juncunol 

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Copyright information

© Indian Academy of Sciences 1988

Authors and Affiliations

  • Gary H. Posner
    • 1
  • Karen A. Canella
    • 1
  • Ernest F. Silversmith
    • 1
  1. 1.Department of ChemistryThe Johns Hopkins UniversityBaltimoreUSA

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