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Resonance

, Volume 8, Issue 6, pp 8–16 | Cite as

Woodward’s synthesis of vitamin B12

  • Adil Ghani Khan
  • S. V. Eswaran
General Article

Abstract

The synthesis of this molecule was a landmark in organic synthesis. It involved the masterful control of shapes of molecules to create 9 chiral centres with known absolute and relative configurations. The concepts of absolute and induced asymmetric synthesis are here explained.

Keywords

Asymmetric synthesis chiral 

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Copyright information

© Indian Academy of Sciences 2003

Authors and Affiliations

  1. 1.Saman ZaarAligarhIndia

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