Effect of low and high doses ofSalmonella enteritidis PT4 on experimentally infected chicks
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Chicks (1-d-old, three groups, each containing 50 chicks) were inoculated with 2×102 and 2×108 CFU ofSalmonella enteritidis; the third group were kept as uninoculated control. Five birds from each group were euthanized at intervals from 6 h to 4 weeks post-inoculation (pi). In the lowdose groupS. enteritidis was isolated from 60% cecal samples at 18 h pi. and from 20% of livers at 3 d pi. Individual variation in the frequency ofS. enteritidis recovery was observed in this group. The clearance of salmonella from the organs was faster in the low-dose group, and salmonella was not isolated from the liver and cecum at 21 and at 27 d, pi, respectively. However, in the high-dose group,S. enteritidis was isolated from all ceca and 80% of liver 6 h pi, and salmonella was detected in the cecum and liver throughout the experiment. Serous typhlitis and unabsorbed yolk sac were the most prevalent lesions in both groups. Granulomatous nodules in the cecum were found occasionally in some cases in both inoculated groups, which can play a role as reservoirs in carrier chicks.
KeywordsPericarditis Bacteriological Examination Microscopic Lesion Chicken Line Organ Colonization
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- Chart H., Rowe B., Baskerville A., Humphrey T.J.: Serological response of chickens toSalmonella enteritidis infection.Epidemiol. Infectol. 104, 63–71 (1990).Google Scholar
- Humphrey T.J., Baskerville A.A., Mawer S., Rowe B., Hopper S.:Salmonella enteritidis PT4 from contents of intact eggs.: a study involving naturally infected hens.Epidemiol. Infectol..103, 415–423 (1989).Google Scholar
- Nagaraja K.V., Pomeroy B.S., Williams, J.E.: Paratyphoid infection. pp. 99–130 in B.W. Calneket al. (Eds):Disease of Poultry. 9th ed. Iowa State University Press, Ames (USA) 1991.Google Scholar
- O’Brien J.D.P.:Salmonella enteritidis infection in broiler chickens.Vet. Rec. 122, 214 (1988).Google Scholar
- Xu, Y.M., Pearson G.R., Hinton M.: The colonization of the alimentary tract and visceral organs of chicks with salmonellas following challengevia the feed: bacteriological findings.Brit. Vet. J. 144, 403–410 (1988).Google Scholar