Biological Trace Element Research

, Volume 10, Issue 3, pp 201–208 | Cite as

Cardiac copper, magnesium, and zinc in recent and old myocardial infarction

  • Nche Zama
  • Robert L. R. Towns
Orginal Articles


X-ray fluorescence spectrometry and atomic absorption spectrometry were used in a quantitative study of zinc, copper, and magnesium in 71 postmortal human hearts. Samples were obtained from individuals who had demonstrated no previous clinical or subsequent pathological findings of myocardial infarction and from victims of a recent or an old infarction. A significant difference (p<0.001) in the elemental levels was observed between the noninfarct and the recent infarct groups. The noninfarct group had higher cardiac levels of all three elements. However, the difference in elemental concentrations between the noninfarct and the old-infarct groups was not significant. Cardiac levels of zinc (p<0.001) and copper (p<0.01) were significantly greater in the old-infarct group than in the recent-infarct group. Magnesium levels were higher in the recent-and-old-infarct group than in the recent infarct group (p<0.01). It is possible that the elements are redistributed during myocardial infarction, and that uptake of these elements (from the serum pool) by the heart may be important in maintaining myocardial integrity and function.

Index Entries

Myocardial analyses, for zinc, copper, and magnesium myocardial infarction, and cardiac zinc, copper, and magnesium copper, zinc, and magnesium in noninfarct, recent-infarct, old-infarct, recent-and-old-infarct myocardium 


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Copyright information

© The Humana Press Inc 1986

Authors and Affiliations

  • Nche Zama
    • 1
  • Robert L. R. Towns
    • 1
  1. 1.Department of ChemistryCleveland State UniversityCleveland

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