Biological Trace Element Research

, Volume 52, Issue 2, pp 117–124 | Cite as

Difference of mineral contents in human intervertebral disks and its age-related change

  • Setsuko Tohno
  • Yoshiyuki Tohno
  • Takeshi Minami
  • Masayo Ichii
  • Yuko Okazaki
  • Masako Utsumi
  • Fumio Nishiwaki
  • Masa-oki Yamada
Original Articles
Received:
Accepted:

Abstract

To establish a difference of the relative contents (RCs) of elements among the cervical, thoracic, and lumbar intervertebral disks and its age-related change, the intervertebral disks between the axis and the sacrum, which were resected from the nine cadavers who died at 53 to 99 yr old, were analyzed by inductively coupled atomic plasma emission spectrometry. It was found that both the RCs of calcium and phosphorus were high in the cervical disks, especially the highest in the disk between the 6th and 7th cervical vertebrae, and lower in the order of the cervical, thoracic, and lumbar intervertebral disks. In regard to the RCs of sulfur and magnesium, there were no significant differences among the cervical, thoracic, and lumbar intervertebral disks. In addition, it was found that both the RCs of calcium and phosphorus in the cervical intervertebral disks started to increase in the sixth decade of life, became the highest in the eighth decade of life, and then decreased.

Index Entries

Intervertebral disk aging calcium phosphorus mineral element human vertebral column 
This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    S. Bernick, R. Cailliet, and B. Levy,Spine 5, 519–524 (1980).PubMedCrossRefGoogle Scholar
  2. 2.
    T. C. Cole, P. Ghosh, and T. K. F. Taylor,Biochim. Biophys. Acta 880, 209–219 (1986).PubMedGoogle Scholar
  3. 3.
    N. Hansen,Lab. Invest. 8, 1242–1265 (1959).PubMedGoogle Scholar
  4. 4.
    R. Silberberg,Gerontologia 17, 236–252 (1971).PubMedCrossRefGoogle Scholar
  5. 5.
    S. W. Wiesel, P. Bernini, and R. H. Rothman,The Aging Spine, Philadelphia, WB Saunders, pp. 1–33 (1982).Google Scholar
  6. 6.
    S. Bernick and R. Cailliet,Spine 7, 97–102 (1982).PubMedCrossRefGoogle Scholar
  7. 7.
    M. D. Brown,Orthop. Clin. North. Am. 2, 359–370 (1971).PubMedGoogle Scholar
  8. 8.
    C. Hirsch and F. Schajowicz,Acta Orthop. Scand. 22, 184–189 (1953).PubMedGoogle Scholar
  9. 9.
    K. Olczyk,Z. Rheumatol. 53, 19–25 (1994).PubMedGoogle Scholar
  10. 10.
    A. Peacock,J. Anat. 86, 162–178 (1952).PubMedGoogle Scholar
  11. 11.
    S. Inoue,J. Jap. Orthop. Assoc. 36, 25–54 (1962) (in Japanese).Google Scholar
  12. 12.
    K. Murayama,J. Jap. Orthop. Assoc. 46, 81–104 (1972) (in Japanese).Google Scholar
  13. 13.
    Y. Tohno, S. Tohno, H. Matsumoto, and K. Naito,J. Nara Med. Assoc. 36, 365–370 (1985) (in Japanese).Google Scholar
  14. 14.
    M. D. Grynpas, K. P. H. Pritzker, and R. G. V. Hancock,Biol. Trace Elem. Res. 13, 333–344 (1987).Google Scholar
  15. 15.
    E. Kondo, K. Ando, and S. Hatori,J. Jap. Orthop. Assoc. 35, 755–764 (1961) (in Japanese).Google Scholar

Copyright information

© Humana Press Inc 1996

Authors and Affiliations

  • Setsuko Tohno
    • 1
  • Yoshiyuki Tohno
    • 1
  • Takeshi Minami
    • 2
  • Masayo Ichii
    • 2
  • Yuko Okazaki
    • 2
  • Masako Utsumi
    • 1
  • Fumio Nishiwaki
    • 1
  • Masa-oki Yamada
    • 1
  1. 1.Department of AnatomyNara Medical UniversityKashihara, NaraJapan
  2. 2.Faculty of Pharmaceutical SciencesKinki UniversityHigashi-OsakaJapan

Personalised recommendations