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Biological Trace Element Research

, Volume 50, Issue 1, pp 79–85 | Cite as

Impairment of motor coordination in mice after ingestion of aluminum chloride

  • Gönül Şahin
  • Tambay Taşkin
  • Kemal Benli
  • Suna Duru
Original Articles

Abstract

The mechanisms of aluminum (Al) neurotoxicity is of increasing interest. Al compounds are known to produce neurological and behavioral abnormalities in some mammalian species. The present study was designed to determine the effects of Al chloride on the skilled motor performance in mice on the rota-rod treadmill. Al chloride, depending on the duration of treatment, produced an impairment of the motor coordination ability in mice.

Index Entries

Aluminum chloride motor coordination rota-rod treadmill 

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Copyright information

© Humana Press Inc. 1995

Authors and Affiliations

  • Gönül Şahin
    • 1
  • Tambay Taşkin
    • 2
  • Kemal Benli
    • 3
  • Suna Duru
    • 1
  1. 1.Department of Toxicology, Faculty of PharmacyHacettepe UniversityAnkaraTurkey
  2. 2.Deva Pharmaceutical CorporationIstanbulTurkey
  3. 3.Department of Neurosurgery, Faculty of MedicineHacettepe UniversityAnkaraTurkey

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