International Journal of Pancreatology

, Volume 17, Issue 1, pp 23–28 | Cite as

Fusion and duplication variants of pancreatic duct system

Clinical and pancreatographic evaluation
  • Generoso Uomo
  • Gianpiero Manes
  • Luigi D'Anna
  • Marco Laccetti
  • Sabato Di Gaeta
  • Pier G. Rabitti


The aim of this study was to assess the incidence of fusion and duplication variants of the pancreatic duct system and their clinical significance. A total of 650 endoscopic retrograde cholangiopancreatography were reviewed; 485 cases with satisfactory imaging of the pancreatic ducts were included in the study. Anatomic variants were observed in 48 patients (9.9%), fusion variants were 54.1% of the cases (22 pancreas divisum and 4 functional divisum), and duplication variants were 45.8% (13 bifurcations of the main pancreatic duct, 4 loop, 2N-shape, 3 ring). Clinical indications to endoscopic cholangiopancreatography were idiopathic acute pancreatitis (33.3%), suspected chronic pancreatitis (18.7%), unexplained abdominal pain (14.5%), suspected pancreatic mass (10.4%), chronic hyperamylasemia (6.2%), and acute biliary pancreatitis (16.6%). Except for acute biliary pancreatitis (significantly more frequent in duplication variants), no statistical difference was observed between the groups with anatomical variants concerning clinical features.

Key Words

Pancreatic ducts anatomical variants pancreas divisum idiopathic acute pancreatitis biliary acute pancreatitis endoscopic cholangiopancreatography 


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Copyright information

© Humana Press Inc 1995

Authors and Affiliations

  • Generoso Uomo
    • 2
  • Gianpiero Manes
    • 2
  • Luigi D'Anna
    • 1
  • Marco Laccetti
    • 2
  • Sabato Di Gaeta
    • 1
  • Pier G. Rabitti
    • 2
  1. 1.RadiologyCardarelli HospitalNapoliItaly
  2. 2.Panereatic Disease Centre, Internal Medicine, XXI Div.Cardarelli HospitalNapoliItaly

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