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Archives of Gynecology and Obstetrics

, Volume 253, Issue 1, pp 37–42 | Cite as

Pregnancy and hereditary spherocytosis

Report of 8 patients and a review
  • A. Pajor
  • D. Lehoczky
  • Z. Szakács
Originals

Summary

As there is only little information on pregnancy complicated by hereditary spherocytosis, we report on 8 patients with this disorder who had a total of 19 pregnancies. 10 pregnancies occurred in patients before splenectomy, and 9 occurred after splenectomy. There were 13 term births, 4 spontaneous abortions and 2 therapeutic abortions. Of the 19 pregnancies, 8 were complicated by anemia and all were in patients without splenectomy. A hemolytic crisis was encountered in 6 pregnancies, and persistent anemia occurred in 2. Transfusion was required in 4 pregnancies. It would appear that pregnancy may precipitate hemolytic anemia but maternal morbidity and fetal outcome seem more favorable after splenectomy than before splenectomy.

Key words

Spherocytosis Hemolytic anemia Pregnancy Splenectomy Fetal outcome 

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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • A. Pajor
    • 1
  • D. Lehoczky
    • 2
  • Z. Szakács
    • 3
  1. 1.2nd Department of Obstetrics and GynecologySenimelweis Medical UniversityBudapestHungary
  2. 2.1st Department of Internal MedicineSenimelweis Medical UniversityBudapestHungary
  3. 3.Obstetric and Gynecologic DepartmentSchöpf-Merei HospitalBudapestHungary

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