The Indian Journal of Pediatrics

, Volume 73, Issue 1, pp 29–32

Maternal genital bacteria and surface colonization in early neonatal sepsis

  • Basavaraj M. Kerur
  • B Vishnu Bhat
  • B. N. Harish
  • S. Habeebullah
  • C. Uday Kumar
Original Article

Abstract

Objective: The study was intended to evaluate the role of maternal genital bacteria and baby's surface colonization in early onset neonatal sepsis.Methods: Babies (born in the hospital of Jawaharlal Institute of Postgraduate Medical Education and Research) who developed clinical signs of sepsis were studied. Swabs were collected for culture from baby's umbilicus, ear, throat in addition to gastric aspirate and blood culture. The genital tract of the mother was also studied for bacterial colonization. The organisms isolated from the maternal genital tract and baby's surface colonization were correlated with those isolated from blood culture by calculating Phi correlation coefficient.Results:Esch coli was the most common organism isolated from maternal genital tract and surface cultures of babies, but Klebseilla-Spp was the most common organism isolated from blood. There was a significant correlation between surface colonization of babies and matermal genital bacteria, so also was baby's surface culture and blood culture. However, correlation between maternal genital bacteria and baby's blood culture was not significant.Conclusion: Surface colonizing bacteria and not maternal genital bacteria are important in early onset neonatal sepsis.

Key words

Neonatal sepsis Surface colonization Maternal genital bacteria 

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References

  1. 1.
    Klein J, Marcy M. Bacterial sepsis and meningitis. In Remington J, Klein J eds.Infectious Diseases of the Fetus and Newborn Infant, Ed 4. Philadelphia, WB Saunders, 1995; 835–890.Google Scholar
  2. 2.
    Beargie R, Priscilla L, Elon T, John D. Perinatal infection and vaginal flora.Am J Obstet Gynecol 1975; 122: 31–33.PubMedGoogle Scholar
  3. 3.
    Rao k, Ramji S, Thirupuram S, Prakash K. Clinical and bacteriological study of normal and inflamed neonatal conjunctivae.Indian Pediatr 1992; 29: 161–165.PubMedGoogle Scholar
  4. 4.
    Bhakoo ON, Agarwal KC, Mahajan MC, Walia BN. Septicemia in infants and children: A bacteriological study.Indian Pediatr 1968; 5: 518–523.PubMedGoogle Scholar
  5. 5.
    Choudhary P, Srivastava G, Agarwal DS, Saini L, Gupta S. Bacteriological study of neonatal infections.Indian Pediatr 1975; 11: 519–528.Google Scholar
  6. 6.
    Mishra JN, Rai MG, Chakraborthy S, Prasad S. Study of neonatal septicemia. Indian.Pediatr 1985; 22: 281–285.Google Scholar
  7. 7.
    Grace GM, Nordin T, Myers M. Infections acquired by young infants.Am J Dis Child 1981; 135: 693–695.Google Scholar
  8. 8.
    Smith RT, Platou ES. Septicemia of new born.Pediatric 1956; 17: 549–553.Google Scholar
  9. 9.
    Schuchat A, Zywicki SS, Dinsmoor MJ. Risk Factors and Opportunities for Prevention of early-onset Neonatal Sepsis: A multicenter Case-Control Study.Pediatric 2000; 105: 21–26.CrossRefGoogle Scholar
  10. 10.
    Jefrerry H, Buth, Metchison, Wigleewert, Pamela JS, Davious A. Early neonatal bacteremia, comparison of Group B Streptococcal, other gram positive and gram negative infection.Arch Dis Child 1977; 52: 683–685.CrossRefGoogle Scholar
  11. 11.
    Mehrotra N, Kumar A, Chansoria M, Kaul K. Neonatal sepsis: correlation of maternal and Neonatal factors to positive bacterial cultures.Indian Pediatr 1985; 22: 275–280.PubMedGoogle Scholar
  12. 12.
    Bhat BV, Pandey KK, Maya R, Reba K. Bacteriological profile of blood culture isolation from neonates.Indian J Maternal Child Health 1994; 5: 114–116.Google Scholar
  13. 13.
    Kishore K, Deorari AK, Meharban singh, Bhujwala RA. Early onset neonatal sepsis-vertical transmission from maternal genital tract.Indian Pediatr 1987; 24: 45–48.PubMedGoogle Scholar
  14. 14.
    Nathoo KJ, Mason PR, Chimbira TH. Neonatal septicemia in Harare Hospital: etiology and risk factors. The Puerperal Sepsis Study Group.Cent Afr J Med 1990; 36: 150–156.PubMedGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2006

Authors and Affiliations

  • Basavaraj M. Kerur
    • 3
  • B Vishnu Bhat
    • 3
  • B. N. Harish
    • 1
  • S. Habeebullah
    • 2
  • C. Uday Kumar
    • 3
  1. 1.Department of MicrobiologyJawaharlal Institute of Postgraduate Medical Education and ResearchPondicherryIndia
  2. 2.Department of Obst and GyanecologyJawaharlal Institute of Postgraduate Medical Education and ResearchPondicherryIndia
  3. 3.Department of PediatricsJawaharlal Institute of Postgraduate Medical Education and ResearchPondicherryIndia

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