The Indian Journal of Pediatrics

, Volume 68, Issue 8, pp 715–717 | Cite as

Neonatal Sepsis:Staphylococcus aureus as the predominant pathogen

Original Article

Abstract

96 consecutive inborn neonates with blood culture proven bacterial sepsis during the period January to June 1997 were studied. Lethargy with refusal of feeds (28%), fever (28%) and respiratory distress (31.3%) were the major presenting features. Half of them (n=48) were of early onset (<48 hours) and the remaining half were of late onset (> 48 hours). Staphylococcus aureus (n=59, 61.5%) was the predominant pathogen and 66% of them were methicillin resistant followed by Klebsiella pnemoniae (n=24, 21.9), Escherichia coli (n=13, 13.5%) and streptococci (n=3, 3.1%). Antibiotic resistance was common, with the sensitivity to various antibiotics being ampicillin 19%, gentamicin 21.6%, cefotaxime 32.8%, amikacin 50%, chloromycetin 59.6% and ciprofloxacin 90.3%.

Key words

Neonatal sepsis Staphylococcus aureus Antimicrobial resistance 

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References

  1. 1.
    Neonatal morbidity and mortality: Report of the National Neonatal-Perinatal Database.Ind Pediatr 1997;34: 1039–1042.Google Scholar
  2. 2.
    Gerdes JS. Clinicopathological approach to the diagnosis of neonatal sepsis.Isr J Med Scien 1994; 30: 430–441.Google Scholar
  3. 3.
    Mondal GP, Mayaraghavan B, Bhat BVet al. Neonatal septicemia among inborn and outborn babies in a referral hospital.Ind J Pediatr 1991; 58: 529–533.CrossRefGoogle Scholar
  4. 4.
    Kathua SP, Das AK, Chatterjee BD. Neonatal septicemia.Ind J Pediatr 1986; 53: 509–514.CrossRefGoogle Scholar
  5. 5.
    Bhakoo ON, Narang A, Kulkarni KN. Neonatal morbidity and mortality in hospital born babies.Ind Pediatr 1975; 12: 443–450.Google Scholar
  6. 6.
    Kaushik, Grover N, Parmer VR, Grover PS, Kaushi KR. Neonatal morbidity in a hospital at Shimla.Ind J Pediatr 1999; 66: 15–19.CrossRefGoogle Scholar
  7. 7.
    Isaacs D, Barfield CP, Grimwood Ket al.. Systemic bacterial and fungal infections in infants in Australian neonatal units. Australian Study Group for neonatal infections.Med J Austr 1995; 162: 198–201.Google Scholar
  8. 8.
    Thomas M, Padmini B, Srimathi G, Sundararajan V, Raju BA. Microbiological profile of neonatal infections in Coimbatore.Ind J Pediatr 1999; 66: 11–14.CrossRefGoogle Scholar
  9. 9.
    Pildes RS, Ramamurthy RS, Vidyasagar D. Effect of triple dye on staphylococcal colonization in the newborn infant.J Pediatr 1973; 82: 887–890.CrossRefGoogle Scholar
  10. 10.
    Coyer WF. Neonatal skin care and the prevention ofS.aureus colonization.Pediatr Res 1975; 9: 339–340.Google Scholar
  11. 11.
    Cookson B. Is it time searching for Methicillin resistantS. aureus.Brit Med J 1997; 314: 664–665.PubMedGoogle Scholar
  12. 12.
    Teare EL. Stop the ritual of tracing colonized people.Brit Med J 1997; 314: 665–666.PubMedGoogle Scholar
  13. 13.
    Neonatal morbidity and mortality. Report of the National Neonatal Perinatal Database.Ind Pediatr 1999; 36: 167–169.Google Scholar
  14. 14.
    Jick S. Ciprofloxacin safety in a pediatric population.Pediatr Inf Dis J 1997; 16: 130–134.CrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2001

Authors and Affiliations

  1. 1.Department of PaediatricsGovernment Kasturiba Gandhi Hospital for Women and ChildrenChennaiIndia

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