Clinical Reviews in Allergy & Immunology

, Volume 15, Issue 3, pp 243–269 | Cite as


Respiratory tract effects
  • Brent E. Van Hoozen
  • Carroll E. Cross
Pulmonary Complications of Recreational Drug Usage

Summary and Conclusions

Daily marijuana smoking has been clearly shown to have adverse effects on pulmonary function and produce respiratory symptomatology (cough, wheeze, and sputum production) similar to that of tobacco smokers. Based on the tobacco experience, decrements in pulmonary function may be predictive of the future development of chronic obstructive pulmonary disease (COPD). However, in the absence of α-l-antitrypsin deficiency, the habitual marijuana-only smoker would likely have to smoke 4–5 joints per day for a span of at least 30 yr in order to develop overt manifestations of COPD.


Chronic Obstructive Pulmonary Disease Tobacco Smoke Clinical Review Respiratory Effect Immunology Volume 
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Copyright information

© Humana Press Inc 1997

Authors and Affiliations

  • Brent E. Van Hoozen
    • 1
  • Carroll E. Cross
    • 1
  1. 1.Division of Pulmonary and Critical Care MedicineUniversity of California at DavisSacramento

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