The Indian Journal of Pediatrics

, Volume 66, Issue 5, pp 681–684

Zinc levels in women and newborns

  • Satyajeet Singh Rathi
  • M. Srinivas
  • J. K. Grover
  • D. Mitra
  • V. Vats
  • J. D. Sharma
Original Article

Abstract

Zinc is an important trace element having a definitive role in the metabolism, growth and development and reproduction. During pregnancy the requirements for zinc increase. This study was designed to evaluate the zinc status of normal women, normal pregnant women and their new-born babies.

Forty normal adult females, 40 normal pregnant women and their newborn babies were randomly selected and their serum and hair zinc levels were analysed using atomic absorption spectrophotometer.

The mean serum and hair zinc levels in normal women were 69.47 ±1.4 μg/dl and 147.45 ± 6.12 μg/g respectively. The mean serum and hair zinc levels in normal pregnant women were 69.0 ± 3.22 μg/dl and 142.83 ± 4.39 μg/g respectively while the mean serum (cord blood) and hair levels in normal new born babies were 72.77 ±5.14 μg/dl and 188.36 ±4.12 μg/g respectively. There was a significant (p < 0.001) decrease in hair zinc levels during pregnancy. There was a significant (p < 0.05) decrease in zinc levels in new born babies when the time interval between the previous delivery and the present delivery was less than 3.4 years.

The results of the present study reinforce the need for zinc supplementation during pregnancy especially if the interval between pregnancies is short.

Key words

Zinc status Pregnancy New born 

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References

  1. 1.
    Hambidge KM, Waltravens RN. Zinc deficiency in infants and pre-adolescent children. In: Prasad AS (ed).Trace Elements in Human Health and Disease. Academic Press, New York 1976; pp 21–32.Google Scholar
  2. 2.
    Lstinen R, Vouri E, Dahlstrom Set al. Zinc, copper and growth status in children and adolescents.Pediatr Tes 1989; 25: 323–326.CrossRefGoogle Scholar
  3. 3.
    Prasad AS. Clinical endocrinological and biochemical effects of zinc deficiency.Clin Endocrinol Metab 1985; 14: 567–589.PubMedCrossRefGoogle Scholar
  4. 4.
    O’Dell BL. Effects of dietary components on zinc bioavailability.Am J Clin Nutr 1969; 22: 1714–1715.Google Scholar
  5. 5.
    The Food and Nutrition Board Research Council. Recommended dietary allowances. 10th edn. Washington DC: National Academy Press, 1989.Google Scholar
  6. 6.
    Hurley LS. Trace elements and teratogenesis.Med Clin North Am 1976; 60: 771–80.PubMedGoogle Scholar
  7. 7.
    Hambidge KM. The role of zinc and other trace metals in pediatric nutrition and health.Pediatr Clin North Aner 1977; 24: 95–105.Google Scholar
  8. 8.
    Golub MS, Gershwin ME, Hurley LSet al. Studies of marginal zinc deprivation in rhesus monkeys II. Pregnancy outcome.Am J Clin Nutr 1984; 39: 879–87.PubMedGoogle Scholar
  9. 9.
    Simmer K, Thompson RPH. Maternal zinc and intrauterine growth retardation.Clin Sci 1985; 68: 395–9.PubMedGoogle Scholar
  10. 10.
    Meadows NJ, Smith MF, Keeling PWNet al. Zinc and small babies.Lancet 1981; 2: 1135–36.PubMedCrossRefGoogle Scholar
  11. 11.
    Swenerton H, Shrader R, Hurley LS. Zinc deficient embryos: reduced thymidine incorporation.Science 1969; 166 : 1041–15.CrossRefGoogle Scholar
  12. 12.
    Hurley LS, Mutch PB. Prenatal and postnatal development after transitory gestational zinc deficiency in rats.J Nutr 1973; 103: 649–656.PubMedGoogle Scholar
  13. 13.
    Jackson MJ. Physiology of zinc: general aspects In : Mills CF (ed.).Zinc in Human Biology. Springer-Verlag, London, 1989; 1–4.Google Scholar
  14. 14.
    Crofton RW, Gvozdanovic D, Gvozdanovic Set al. Inorganic zinc and the intestinal absorption of ferrous iron.Am J Clin Nutr 1989; 50: 141–4.PubMedGoogle Scholar
  15. 15.
    Fuller NJ, Bates CJ, Evans PHet al. High folate intakes related to zinc status in preterm infants.Eur J Pediatr 1992; 151: 51–3.PubMedCrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 1999

Authors and Affiliations

  • Satyajeet Singh Rathi
    • 1
  • M. Srinivas
    • 2
  • J. K. Grover
    • 1
  • D. Mitra
    • 2
  • V. Vats
    • 1
  • J. D. Sharma
    • 3
  1. 1.Departments of PharmacologyAll India Institute of Medical SciencesNew Delhi
  2. 2.Departments of Paediatric SurgeryAll India Institute of Medical SciencesNew Delhi
  3. 3.School of Environmental SciencesJawaharlal Nehru UniversityNew Delhi

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