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Korean Journal of Chemical Engineering

, Volume 20, Issue 6, pp 1073–1076 | Cite as

Caffeine Molecular Imprinted Microgel Spheres by Precipitation Polymerization

  • Dexian Wang
  • Seung Pyo Hong
  • Gengliang Yang
  • Kyung Ho Row
Articles

Abstract

Imprinted uniform microgel spheres were prepared by precipitation polymerization. Acetonitrile was used as the dilute solvent with MAA as the monomer, EDMA as the crosslinker and caffeine as the print molecule. Comparison of caffeine adsorption on molecular imprinted and blank microgel spheres was made. Langmuir model was used to fit the adsorption data. It was found that the caffeine imprinted microgel spheres show specific binding sites to the target molecules. A binding study of caffeine on imprinted microgel spheres was made by Scatchard analysis; the dissociation constants (KD) and the maximum binding capacity were KD= 1.84×10−4mol/L,Q max = 16.98 μmol/g for high affinity binding site and KD=1.33×l0−3 mol/L, Qmax=46.84 μmol/g for lower affinity binding site, respectively This microgel spheres can be useful affinity adsorbents in further applications.

Key words

Molecular Imprinted Polymers Microgel Spheres Caffeine 

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Copyright information

© Korean Institute of Chemical Engineering 2003

Authors and Affiliations

  • Dexian Wang
  • Seung Pyo Hong
    • 1
  • Gengliang Yang
    • 2
  • Kyung Ho Row
    • 1
  1. 1.Center for Advanced Bioseparation Technology, Department of Chemical EngineeringInha UniversityIncheonKorea
  2. 2.Department of ChemistryHebei UniversityBaodingP. R. China

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