Stem Cell Reviews

, Volume 2, Issue 4, pp 277–287 | Cite as

Interspecies somatic cell nuclear transfer and preliminary data for horse-cow/mouse iSCNT

  • R. Tayfur Tecirlioglu
  • Jitong Guo
  • Alan O. TrounsonEmail author


Nuclear transfer (NT) experiments in mammals have demonstrated that adult cells are genetically equivalent to early embryonic cells and the reversal of the differentiated state of a cell to another that has characteristics of the undifferentiated embryonic state can be defined as nuclear reprogramming. The feasiblity of interspecies somatic cell NT (iSCNT) has been demonstrated by blastocyst formation and the production of offspring in a number of studies. Embryo and oocyte availability is a major limiting factor in conducting NT to obtain, blastocysts for both reproductive NT studies in genetically endangered animals and in embryonic stem cell derivation for species such as the horse and human. One approach to generate new embryonic stem cells in human as disease models, or in species where embryos and oocytes are not widely available, is to use oocytes from another species. Utilization of oocytes for recipient cytoplasts from other species that are accessible and abundant, such as the cow and rabbit, would greatly benefit ongoing research on reprogramming and stem cell sciences. The use of iSCNT is an exciting possibility for species with limited availability of oocytes as well as for endangered or exotic species where assisted reproduction is needed. However, the mechanisms involved in nuclear reprogramming by the oocyte are still unknown and the extent of the “universality” of ooplasmic reprogramming of development remains under investigation.

Index Netries

Bovine cloning cow cross-species embryonic stem cells equine horse human interspecies mouse murine nuclear transfer pluripotentiality xenogenic 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Rauber A. Zool Anz 1886;6:166–171.Google Scholar
  2. 2.
    Rostand J. Rev Sci 1943;81:454–456.Google Scholar
  3. 3.
    McKinnell RG. In Cloning: Nuclear Transplantation in Amphibia. University of Minnesota Press, Minneapolis 1978; p. 319.Google Scholar
  4. 4.
    Mulnard J. CR Acad Sci Hebd Seances Acad Sci D 1973;276:379–381.Google Scholar
  5. 5.
    Mystkowska ET. J Embryol Exp Morphol 1975;33:731–744.PubMedGoogle Scholar
  6. 6.
    Gardner RL, Johnson MH. Nat New Biol 1973;246:86–89.PubMedGoogle Scholar
  7. 7.
    Gardner RL, Johnson MH. In Investigation of cellular interaction and deployment in the early mammalian embryo using interspecific chimaeras between the rat and mouse, in Cell Patterning, Ciba Found Symp, Excerpta Medica, North Holland, Amsterdam 1975;29: pp. 183–200.Google Scholar
  8. 8.
    Rossant J, Frels WI. Science 1980;208:419–421.PubMedGoogle Scholar
  9. 9.
    Fehilly CB, Willadsen SM, Tucker EM. Nature 1984;307:634–636.PubMedGoogle Scholar
  10. 10.
    Polzin VJ, Anderson DL, Anderson GB, et al. J Anim Sci 1987; 65:325–330.PubMedGoogle Scholar
  11. 11.
    Summers PM, Shelton JN, Bell K. Anim Reprod Sci 1983;6:91–102.Google Scholar
  12. 12.
    Williams TJ, Munro RK, Shelton JN. Reprod Fertil Dev 1990;2: 385–394.PubMedGoogle Scholar
  13. 13.
    Fehilly CB, Willadsen SM. Oxf Rev Reprod Biol 1986;8:379–413.PubMedGoogle Scholar
  14. 14.
    Rossant J, Mauro VM, Croy BA. J Embryol Exp Morphol 1982;69: 141–149.PubMedGoogle Scholar
  15. 15.
    Dominko T, Mitalipova M, Haley B, et al. Biol Reprod 1999;60: 1496–1502.PubMedGoogle Scholar
  16. 16.
    Lanza RP, Cibelli JB, Diaz F, et al. Cloning 2000;2:79–90.PubMedGoogle Scholar
  17. 17.
    Dindot SV, Farin PW, Farin CE, et al. Biol Reprod 2004;71: 470–478.PubMedGoogle Scholar
  18. 18.
    Meirelles FV, Bordignon V, Watanabe Y, et al. Genetics 2001;158: 351–356.PubMedGoogle Scholar
  19. 19.
    Hiendleder S., Wolf K, Bruggerhoff K, et al. Therigenology 2001;57:419.Google Scholar
  20. 20.
    Steinborn R, Schinogl P, Wells DN, Bergthaler A, Muller M, Brem G. Genetics 2002;162:823–829.PubMedGoogle Scholar
  21. 21.
    Sansimena MJ, Hylan D, Hebert K, Denniston RS, Godke RA. Theriogenology 2005;63:1081–1091.Google Scholar
  22. 22.
    Loi P, Ptak G, Barboni B, Fulka J, Jr, Cappai P, Clinton M. Nat Biotechnol 2001;19:962–964.PubMedGoogle Scholar
  23. 23.
    Woods GL, White KL, Vanderwall DK, et al.Science 2003;301:1063.PubMedGoogle Scholar
  24. 24.
    Gomez MC, Pope CE, Giraldo A, et al. Clon Stem Cells 2004;6: 247–258.Google Scholar
  25. 25.
    Gomez MC, Pope CE, Giraldo A, et al. Reprod Fert Dev 2004;16: 141–142.Google Scholar
  26. 26.
    Gomez Mc, Pope CE, Cole A, Dresser BL. Proc 15th Cong Anim Reprod, Porto Seguro, Brazil, 2004;562.Google Scholar
  27. 27.
    Chen T, Zhang YL, Jiang Y, et al. Mol Reprod Dev 2006;73:313–317.PubMedGoogle Scholar
  28. 28.
    Loring JF, Rao MS. Stem Cell 2006;24:145–150.Google Scholar
  29. 29.
    Munsie MJ, Michalska AE, O'Brien CM, Trounson AO, Pera MF, Mountford PS. Curr Biol 2000;10:989–992.PubMedGoogle Scholar
  30. 30.
    Kawase E, Yamazaki Y, Yagi T, Yanagimachi R, Pedersen RA. Genesis 2000;28:156–163.PubMedGoogle Scholar
  31. 31.
    Wakayama S, Ohta H, Kishigami S, et al. Biol Reprod 2005; 72:932–936.PubMedGoogle Scholar
  32. 32.
    Wakayama T. Oncol Res 2003;13:309–314.PubMedGoogle Scholar
  33. 33.
    Wakayama T. Estabishment of nuclear transfer embryonic stem cell lines from adult somatic cells by nuclear transfer and its application. Ermst Schering Res Found Workshop, pp. 111–123, 2006.Google Scholar
  34. 34.
    Wakayama T, Tabar V, Rodriguez I, Perry AC, Studer L, Mombaerts P. Science 2001;292:740–743.PubMedGoogle Scholar
  35. 35.
    Wakayama S, Jakt ML, Suzuki M, et al. Stem Cells 2006;24:2023–2033.PubMedGoogle Scholar
  36. 36.
    Hochedlinger K, Jaenisch R. Nature 2002;415:1035–1038.PubMedGoogle Scholar
  37. 37.
    Rideout WM, 3rd, Hochedlinger K, Kyba M, Daley GQ, Jaenisch R, Cell 2002;109:17–27.PubMedGoogle Scholar
  38. 38.
    Wang L, Duan E, Sung LY, Jeong BS, Yang X, Tian XC. Biol Reprod 2005;73:149–155.PubMedGoogle Scholar
  39. 39.
    Chen Y, He ZX, Liu A, et al. Cell Res 2003;13:251–263.PubMedGoogle Scholar
  40. 40.
    Manadavilli A. Nat Med 2006;12:265.Google Scholar
  41. 41.
    Vogel G. Science 2006;313:155–156.Google Scholar
  42. 42.
    Marshall E. Science 1998;282:1390–1391.PubMedGoogle Scholar
  43. 43.
    Kelly DP, Scarpulla RC. Genes Dev 2004;18:357–368.PubMedGoogle Scholar
  44. 44.
    Ross IK. Ann NY Acad Sci 2004;1019:581–584.PubMedGoogle Scholar
  45. 45.
    Kenyon L, Moraes CT. Proc Natl Acad Sci USA 1997;94: 9131–9135.PubMedGoogle Scholar
  46. 46.
    Matveeva NM, Shilov AG, Kaftanovskaya EM, et al. Mol Reprod Dev 1998;50:128–138.PubMedGoogle Scholar
  47. 47.
    Tada M, Takahama Y, Abe K, Nakatsuji N, Tada T. Curr Biol 2001;11:1553–1558.PubMedGoogle Scholar
  48. 48.
    Pells S, Di Domenico AI, Gallagher EJ, McWhir J. Clon Stem Cells 2002;4:331–338.Google Scholar
  49. 49.
    Ying QL, Nichols J, Evans EP, Smith AG. Nature 2002;416:545–548.PubMedGoogle Scholar
  50. 50.
    Do JT, Scholer HR. Stem Cells 2004;22:941–949.PubMedGoogle Scholar
  51. 51.
    Pralong D, Mrozik K, Occhiodoro F, et al. ClonStem Cells 2005;y:265–271.CrossRefGoogle Scholar
  52. 52.
    Terada N, Hamazaki T, Oka M, et al. Nature 2002;416:542–545.PubMedGoogle Scholar
  53. 53.
    Tada M, Tada T, Lefebvre L, Barton SC, Surani MA. Embo J 1997; 16:6510–6520.PubMedGoogle Scholar
  54. 54.
    Cowan CA, Atienza J, Melton DA, Eggan K. Science 2005;309: 1369–1373.PubMedGoogle Scholar
  55. 55.
    Strelchenko N, Kukharenko V, Shkumatov A, Verlinsky O, Kuliev A, Verlinsky Y. Reprod Biomed Online 2006;12:107–111.PubMedCrossRefGoogle Scholar
  56. 56.
    Taranger CK, Noer A, Sorensen AL, Hakelien AM, Boquest AC, Collas P. Mol Biol Cell 2005;16:5719–5735.PubMedGoogle Scholar
  57. 57.
    Flasza M, Shering AF, Smith K, Andrews PW, Talley P, Johnson PA. Clon Stem Cells 2003;5:339–354.Google Scholar
  58. 58.
    Hansis C, Barreto G, Maltry N, Niehrs C. Curr Biol 2004;14: 1475–1480.PubMedGoogle Scholar
  59. 59.
    Simonsson S, Gurdon JB. Cell Cycle 2005;4:513–515.PubMedGoogle Scholar
  60. 60.
    Clark MA, Shay JW. Nature 1982;295:605–607.PubMedGoogle Scholar
  61. 61.
    Iwakura Y, Nozaki M, Asano M, et al. Cell 1985;43:777–791.PubMedGoogle Scholar
  62. 62.
    Zuckerman SH, Solus JF, Gillespie FP, Eisenstadt JM. Somatic Cell Mol Genet 1984;10:85–91.Google Scholar
  63. 63.
    Hayashi J, Tagashira Y, Yoshida MC. Exp Cell Res 1985;160:387–395.PubMedGoogle Scholar
  64. 64.
    Clayton DA, Teplitz RL, Nabholz M, Dovey H, Bodmer W. Nature 1971;234:560–562.PubMedGoogle Scholar
  65. 65.
    De Francesco L, Attardi G, Croce CM. Proc Natl Acad Sci USA 1980e;77:4079–4083.PubMedGoogle Scholar
  66. 66.
    Giles RE, Stroynowski I, Wallace DC. Somatic Cell Genet 1980;6:543–554.PubMedGoogle Scholar
  67. 67.
    McKenzie M, Trounce I. J Biol Chem 2000;275:31,514–31,519.Google Scholar
  68. 68.
    McKenzie M, Chiotis M, Pinkert CA, Trounce IA. Mol Biol Evol 2003;20:1117–1124.PubMedGoogle Scholar
  69. 69.
    Yamaoka M, Isobe K, Shitara H, Yonekawa H, Miyabayashi S, Hayashi JI. Genetics 2000;155:301–307.PubMedGoogle Scholar
  70. 70.
    Dey R, Barrientos A, Moraes CT. J Biol Chem, 2000;275: 31,520–31,527.Google Scholar
  71. 71.
    Rinaudo P, Niven-Fairchild T, Buradagunta S, Massobrio M, Revelli A, Keefe DL. Fertil Steril 1999;71:912–918.PubMedGoogle Scholar
  72. 72.
    Shitara H, Kaneda H, Sato A, et al. Genetics 2000;156:1277–1284.PubMedGoogle Scholar
  73. 73.
    Pinkert CA, Irwin MH, Johnson LW, Moffatt RJ. Transgenic Res 1997;6:379–383.PubMedGoogle Scholar
  74. 74.
    Irwin MH, Johnson LW, Pinkert CA. Transgenic Res 1999;8:119–123.PubMedGoogle Scholar
  75. 75.
    Barrientos A, Kenyon L, Moraes CT. J Biol Chem 1998;273: 14,210–14,217.Google Scholar
  76. 76.
    Evans MJ, Gurer C, Loike JD, Wilmut I, Schnieke AE, Schon EA. Nat Genet 1999;23:90–93.PubMedGoogle Scholar
  77. 77.
    Steinborn R, Zakhartchenko V, Jelyazkov J, et al. FEBS Lett 1998;426:352–356.PubMedGoogle Scholar
  78. 78.
    Steinborn R, Zakhartchenko V, Wolf E, Muller M, Brem G. FEBS Lett 1998;426:357–361.PubMedGoogle Scholar
  79. 79.
    Hiendleder S, Schmutz SM, Erhardt, G, Green RD, Plante Y. Mol Reprod Dev 1999;54:24–31.PubMedGoogle Scholar
  80. 80.
    Takeda K, Takahashi S, Onishi A, Goto Y, Miyazawa A, Imai H. J Reprod Fertil 1999;116:253–259.PubMedCrossRefGoogle Scholar
  81. 81.
    Hiendleder S, Zakhartchenko V, Wenigerkind H, et al. Biol Reprod 2003;68:159–166.PubMedGoogle Scholar
  82. 82.
    Chen DY, Wen DC, Zhang YP, et al. Biol Reprod. 2002;67:637–642.PubMedGoogle Scholar
  83. 83.
    Steinborn R, Schinogl P, Zakhartchenko V, et al. Nat Genet 2000;25:255–257.PubMedGoogle Scholar
  84. 84.
    Jiang Y, Liu SZ, Zhang YL, Jiang MX, Sun QY, Chen DY. Acta Biochim Biophys Sin (Shanghai). 2004;36:371–374.CrossRefGoogle Scholar
  85. 85.
    Chang KH, Lim JM, Kang SK, Lee BC, Moon SY, Hwang WS. Fertil Steril. 2003;80:1380–1387.PubMedGoogle Scholar
  86. 86.
    Yang CX, Han ZM, Wen DC, et al. Reproduction. 2004;127:201–205.PubMedGoogle Scholar
  87. 87.
    Inoue K, Ogonuki N, Yamamoto Y, et al. Genesis. 2004;39:79–83.PubMedGoogle Scholar
  88. 88.
    Do JT, Lee JW, Lee BY, et al. Biol Reprod 2002;67:555–560.PubMedGoogle Scholar
  89. 89.
    Takeda K, Akagi S, Kaneyama K, et al. Mol Reprod Dev. 2003;64: 429–437.PubMedGoogle Scholar
  90. 90.
    Meirelles FV, Smith LC. Genetics. 1998;148:877–883.PubMedGoogle Scholar
  91. 91.
    Van Blerkom J, Sinclair J, Davis P. Hum Reprod. 1998; 13:2857–2868.PubMedGoogle Scholar
  92. 92.
    Piko L, Taylor KD. Dev Biol. 1987;123:364–374.PubMedGoogle Scholar
  93. 93.
    St John JC, Lloyd RE, Bowles EJ, Thomas EC, El Shourbagy S. Reproduction. 2004;127:631–641.PubMedGoogle Scholar
  94. 94.
    Yang CX, Han ZM, Wen DC, et al. Mol Reprod Dev. 2003; 65:396–401.PubMedGoogle Scholar
  95. 95.
    Nagao Y, Totsuka Y, Atomi Y, et al. Theriogenology 1997;47:233.Google Scholar
  96. 96.
    Takeda K, Tasai M, Iwamoto M, et al. Biol Reprod. 2005;72: 1397–1404.PubMedGoogle Scholar
  97. 97.
    Vajta G, Lewis IM, Hyttel P, Thouas GA, Trounson AO. Cloning 2001;3:89–95.PubMedGoogle Scholar
  98. 98.
    Tecirlioglu RT, Cooney MA, Lewis IM, et al. Reprod Fert Dev 2005;17:573–585.Google Scholar
  99. 99.
    Tecirlioglu RT, French AJ, Lewis IM, et al. Reprod Fert Dev 2004;15:361–366.Google Scholar
  100. 100.
    Hall VJ, Ruddock NT, Cooney MA, et al. Theriogenology 2006;65:424–440.PubMedGoogle Scholar
  101. 101.
    Tecirlioglu RT, Cooney MA, Korfiatis NA, et al. Theriogenology 2006;65:1783–1799.PubMedGoogle Scholar
  102. 102.
    Fischer Lindahl K, Hermel E, Loveland BE, Wang CR. Annu Rev Immunol. 1991;9:351–372.PubMedGoogle Scholar
  103. 103.
    Spees JL, Olson SD, Whitney MJ, Prockop DJ. Proc Natl Acad Sci USA 2006;103:1283–1288.PubMedGoogle Scholar
  104. 104.
    Vajta G, Peura TT, Holm P, et al. Mol Reprod Dev 2000;55:256–264.PubMedGoogle Scholar
  105. 105.
    Kim HS, Oh SK, Park YB, et al. Stem Cells 2005;23:1228–1233.PubMedGoogle Scholar
  106. 106.
    Lyrawati D. PhD Thesis, Gene targeting in cellular mitochondria. Monash Institute of Reproduction and Development, Monash University, Melbourne, Australia, 2003.Google Scholar
  107. 107.
    Kang YK, Koo DB, Park JS, Choi YH, Lee KK, Han YM. FEBS Lett 2001;499:55–58.PubMedGoogle Scholar
  108. 108.
    Tecirlioglu RT, Lacham-Kaplan O, Trounson AO. Reprod Fert Dev 2002;14:471–478.Google Scholar
  109. 109.
    Ribas R, Oback B, Ritchie W, et al. Clon Stem Cells 2005;7:126–138.Google Scholar
  110. 110.
    Ribas R, Oback B, Ritchie W, et al. Clon Stem Cells 2006;8:10–15.Google Scholar
  111. 111.
    Kitiyanant K, Saikhun J, Jaroensuwan M, Thaiying S, Pavasuthipaisit K. Theriogenology 2000;53:226.Google Scholar
  112. 112.
    Kitiyanant Y, Saikhun J, Chaisalee B, White KL, Pavasuthipaisit K. Clon Stem Cells 2001;3:97–104.Google Scholar
  113. 113.
    Saikhun J, Pavasuthipaisit K, Jaruansuwan M, Kitiyanant Y. Theriogenology 2002;57:1829–1837.PubMedGoogle Scholar
  114. 114.
    Atabay EC, Takahashi Y, Katagiri S, Nagano M, Koga A, Kanai Y. Theriogenology 2004;61:15–23.PubMedGoogle Scholar
  115. 115.
    Lu F, Shi D, Wei J, Yang S, Wei Y. Theriogenology. 2005;64: 1309–1319.PubMedGoogle Scholar
  116. 116.
    Singla SK, Manik RS, Madan ML. Indian J Exp Biol 1997;35: 1273–1283.PubMedGoogle Scholar
  117. 117.
    Murakami M, Otoi T, Wongsrikeao P, Agung B, Sambuu R, Suzuki T. Clon Stem Cells 2005;7:77–81.Google Scholar
  118. 118.
    Li Y, Dai Y, Du W, et al. Mol Reprod Dev 2006;73:189–195.PubMedGoogle Scholar
  119. 119.
    Su L, Du FL, Sung LY, et al. Reprod Fert Dev 2004;1:183.Google Scholar
  120. 120.
    Damiani P, Wirtu G, Miller F, Cole A, Pope C, Godke RA. Theriogenology 2003;59:390.Google Scholar
  121. 121.
    Lee B, Wirtu G, Andrews J, Poole K, Dresser B, Bavister B. Theriogenology 2002;57:586.Google Scholar
  122. 122.
    Bui LC, Vignon X, Campion E, et al. Theriogenology 2002;57:427.Google Scholar
  123. 123.
    Uoc NT, Tyl LV, Tuoc D, et al. Theriogenology 2002;57:437.Google Scholar
  124. 124.
    Park HS, Lee MY, Park JK, et al. Theriogenology 2003;59:278.Google Scholar
  125. 125.
    Matshikiz M, Bartels P, Vajta G, et al. Reprod Fert Dev 2004;16: 150–151.Google Scholar
  126. 126.
    Sansinena MJ, Taylor P, Taylor S, Denniston RS, Godke RA. Theriogenology 2003;59:287.Google Scholar
  127. 127.
    Yoon JT, Cho EJ, Han KY, Shim S. Theriogenology 2001;55:298.Google Scholar
  128. 128.
    Lagutina I, Brunetti D, Lazzari G, Galli C. Reprod Fert Dev 2005;18:134–135.Google Scholar
  129. 129.
    Li GP, Siedel GE, Squires EL. Theriogenology 2002;57:432.Google Scholar
  130. 130.
    Sansinena MJ, Reggio BC, Denniston RS, Godke RA. Theriogenology 2002;58:775–777.Google Scholar
  131. 131.
    Hinrichs K, Shin T, Love CC, Varner DD, Westhusin ME. Proc 5th Int Symp Equine Emb Trans, Havermeyer Foundation Monograph Series, R & W Publications Limited: Newmarket, Suffolk, UK. 2000;3:43–44.Google Scholar
  132. 132.
    Reggio BC, Sansinena MJ, Cochran R, et al. Proc 5th Int Symp Equine Emb Trans, Havermeyer Foundation Monograph Series, R & W Publications Limited: Newmarket, Suffolk, UK. 2000;3:45–46.Google Scholar
  133. 133.
    Shi W, Yang F, Wolf E, Zakharchenko V. Reprod Fert Dev 2005;18:128.Google Scholar
  134. 134.
    Saeki K, Maeda M, Horii T, et al. Therigenology 2002;57:446.Google Scholar
  135. 135.
    Kim NH, Shin MR, Park SH. Reprod Fert Dev 2004;16:144–145.Google Scholar
  136. 136.
    Nieminen PM, Aho M, Kananen-Anttila K, Reinikainen E. Reprod Fert Dev 2004;17:179.Google Scholar
  137. 137.
    Koo BS, Son HY, Kim MG, Lee CK. Theriogenology 2003;59:266.Google Scholar
  138. 138.
    Hwang WKK, Kim G, Jin Y, et al. Theriogenology 2001;55:271.Google Scholar
  139. 139.
    Ty LV, Hahn NV, Uoc NT, Duc NH, Thanh NT, Bui LC. Theriogenology 2003;59:290.Google Scholar
  140. 140.
    Kim TM, Park TS, Shin SS, Han JY, Moon SY, Lim JM. Fertil Steril 2004;82:957–959.PubMedGoogle Scholar
  141. 141.
    Zavos PM, Illmensee K. Arch Androl 2006;52:243–254.PubMedGoogle Scholar
  142. 142.
    Zavos PM. Reprod Biomed Online 2003;6:397–398.PubMedCrossRefGoogle Scholar
  143. 143.
    Zavos PM, Illmensee K. Fertil Steril 2003;80:19–20.Google Scholar
  144. 144.
    Illmensee K, Levanduski M, Zavos PM. Fertil, Steril 2006;85:1248–1260.Google Scholar
  145. 145.
    Lanza RP, Cibelli JB, West MD. Nat Med 1999;5:975–977.PubMedGoogle Scholar
  146. 146.
    Chang KM, Lim JM, Kang SK, Lee BC, Moon SY, Hwang WS. Fertil Steril 2004;82:960–962.PubMedGoogle Scholar
  147. 147.
    Ikumi S, Sawai K, Takeuchi Y, et al. Clon Stem Cells 2004;6: 284–293.Google Scholar
  148. 148.
    Sophon S, Tasripoo K, Srisakwattana K. Buffalo Bull 2002;21: 83–88.Google Scholar
  149. 149.
    Williams B, Shin T, Liu L, et al. Theriogenology 2002;57:457.Google Scholar
  150. 150.
    White KL, Bunch TD, Mitalipov S, Reed WA. Cloning 1999;1: 47–54.PubMedGoogle Scholar
  151. 151.
    Hamilton HM, Kleemann DO, Maddocks S, Rudiger SR, Walker SK, Peura TT. Theriogenology 2003;59:255.Google Scholar
  152. 152.
    Hamilton HM, Peura TT, Laurincik, J, Walker SK, Maddocks S, Maddox-Hyttel P. Mol Reprod Dev 2004;69:117–125.PubMedGoogle Scholar
  153. 153.
    Woods GL, White KL, Vanderwall DK, et al Theriogenology 2002;58:779–782.Google Scholar
  154. 154.
    Waksmundzka M. J Exp Zool 1994;269:551–559.PubMedGoogle Scholar
  155. 155.
    Thongphakdee A, Numchaisrika P, Omsongkram S, et al. Reprod Domest Anim 2006;41:219–226.PubMedGoogle Scholar
  156. 156.
    Gomez MC, Pope CE, Cole A, Dresser BL. Proc 15th Int Cong Anim Reprod, Porto Seguro Brazil, 562.Google Scholar
  157. 157.
    Gomez MC, Jenkins JA, Giraldo A, et al. Biol Reprod 2003;69:1032–1041.PubMedGoogle Scholar
  158. 158.
    Kong IK, Lee HS, Kim NH, Kim LH, Shin HD, Yin XJ. Reprod Fert Dev 2005;18:133.Google Scholar
  159. 159.
    Lorthongpanich C, Laowtammathron C, Muenthaisong, S, et al. Reprod Fertil Dev 2004;16:149–150.Google Scholar
  160. 160.
    Yin XJC, Choi EG, Cho SJ, et al. Reprod Fert Dev 2005;18:262–263.Google Scholar
  161. 161.
    Gomez MC, Pope CE, Lyons L, et al. Reprod Fert Dev 2005;18:144.Google Scholar
  162. 162.
    Wen DC, Bi CM, Xu Y, et al. J Exp Zoolog A Comp Exp Biol 2005;303:689–697.PubMedGoogle Scholar
  163. 163.
    Wen DC, Yang CX, Cheng Y, et al. Mol Reprod Dev 2003;66:38–45.PubMedGoogle Scholar
  164. 164.
    Thongphakdee A, Numchaisrika P, Chatdarong K, et al. Thai J Vet Med 2006;53:40.Google Scholar
  165. 165.
    Hosoi Y, Yamochi T, Kawata N, et al. Reprod Fertil Dev 2006;18:128.Google Scholar
  166. 166.
    Hosoi Y, Yamochi T, Teramura T, et al. Symp. Cell Biol Early Emb, Gold Coast Convention & Exhibition Centre, Broadbeach, Australia 2006, 18.Google Scholar
  167. 167.
    Numchaisrika P, Rungsiwirwut R, Thongpakdee A, Techakumphu M. Reprod Fert Dev 2004;17:179–180.Google Scholar
  168. 168.
    Li JS, Han ZM, Zhu ZY, et al. Shi Yan Sheng Wu Xue Bao 2002;35:62–65.PubMedGoogle Scholar
  169. 169.
    Wang H, Zheng RZ, Lian L, Xu Y, An LJ, Chen DY. Shi Yan Sheng Wu Xue Bao 2003;36:145–148.PubMedGoogle Scholar
  170. 170.
    Techakumphu M, Numchaisrikha P, Thongphagdee A, Omsongkram S. Thai J Vet Med 2006;53:112.Google Scholar
  171. 171.
    Jiang Y, Chen T, Nan CL, Ouyang YC, Sun QY, Chen DY. Zygote 2005;13:233–240.PubMedGoogle Scholar
  172. 172.
    Chen DY, Sun QY, Liu JL, et al. Sci China (Series C) 1999;29: 324–330.Google Scholar
  173. 173.
    Jiang MX, Yang CX, Zhang LS, et al. Zygote 2004;12:315–320.PubMedGoogle Scholar
  174. 174.
    Li J, Chen D, Han Z, et al. China Sci Bull 2002;47:467–469.Google Scholar
  175. 175.
    Zhao ZJ, Ouyang YC, Nan CL, et al. J Reprod Dev 2006;52:449–459.PubMedGoogle Scholar
  176. 176.
    Liu SZ, Zhou ZM, Chen T, et al. Mol Reprod Dev 2004;69: 296–302.PubMedGoogle Scholar
  177. 177.
    Zhou Q, Xiechao H, Chenhui D, et al. In vitro development of interspecies cloned embryos. Society for the Study of Reproduction, Vancouver BC. Canada, 2004, 618.Google Scholar
  178. 178.
    Trounce IA, McKenzie M, Cassar CA, et al. J Bioenerg Biomembr 2004;36:421–427.PubMedGoogle Scholar
  179. 179.
    Inoue K, Ito S, Takai D, et al. J Biol Chem 1997;272: 15,510–15,515.Google Scholar
  180. 180.
    Wakayama S. Kishigami S, Nguyen VT, et al. Proc. 1st Asian Reprod Biotech Soc, Hochiminh City, Vietnam, April 12–14, 2004, 58.Google Scholar

Copyright information

© Humana Press Inc 2006

Authors and Affiliations

  • R. Tayfur Tecirlioglu
    • 1
  • Jitong Guo
    • 1
  • Alan O. Trounson
    • 1
    Email author
  1. 1.Monash Immunology and Stem Cell Laboratories (MISCL), Science Technology Research and Innovation Precinct (STRIP), Building 75Monash UniversityClaytonAustralia

Personalised recommendations