Magma

, Volume 1, Issue 1, pp 21–34 | Cite as

Evaluation of the pulmonary vasculature with three-dimensional magnetic resonance imaging techniques

  • Piotr A. Wielopolski
  • E. Mark Haacke
  • Lee P. Adler
Papers
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Abstract

Cardiac and respiratory motion during the long acquisition times required in 3d magnetic resonance imaging (MRI) can lead to excessive image degradation and consequently poor diagnosis and interpretation in the thoracic region. This paper addresses the issue of obtaining good image quality with 3d gradient echo (GE) imaging in the study of the pulmonary vascular system and its diseases. To study the pulmonary vascular system two approaches have been considered. First, a proton density/inflow weighted scan consisting of a syncopated 3d FLASH acquisition is used to provide a 3d pulmonary angiogram. Secondly, aT 1 weighted scan using 3d IR-FLASH (inversion recovery FLASH) helps in determining the presence of pulmonary emboli. Multiple acquisitions and rectangular field of view are utilized to pseudogate to the respiratory period in order to reduce motion artifacts while keeping reasonable imaging times. Technical aspects on data collection during the approach to equilibrium and acquisition strategies in the presence of thoracic motion and its impact on vessel resolution are addressed. The method has proven successful for imaging volunteers and, more recently, in obtaining useful clinical information.

Keywords

MRI 3d-MRI FLASH gradient echo imaging fast MRI angiography pulmonary vasculature thorax flow MRI TI MRI pulmonary emboli patient studies 
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References

  1. 1.
    Nishimura DG, Macovski A, Pauly JM (1986) Magnetic resonance angiography.IEEE Transactions in Medical Imaging,MI-5: 140–151.CrossRefGoogle Scholar
  2. 2.
    Haacke EM, Lenz GW (1987) Improving image quality in the presence of motion by using rephasing gradients.American Journal of Roentgenology,148: 1251–1258.PubMedGoogle Scholar
  3. 3.
    Farzaneh F, Riederer SJ, Lee JN, Tasciyan T, Wright RC, Spritzer CE (1989) MR fluoroscopy: Initial clinical studies.Radiology 171: 545–549.PubMedGoogle Scholar
  4. 4.
    Bullock PR, Mansfield P, Gowland P, Worthington BS, Firth JL (1991) Dynamic imaging of contrast enhancement in brain tumours.Mag Reson Med 19: 293–298.CrossRefGoogle Scholar
  5. 5.
    Moore EH, Gamsu G, Webb WR, Stulbarg MS (1984) Pulmonary embolus: Detection and follow up using magnetic resonance.Radiology 153: 471–472.PubMedGoogle Scholar
  6. 6.
    Gamsu G, Hirji M, Moore EH, Webb WR, Brito A (1984) Experimental pulmonary emboli detected using magnetic resonance.Radiology 153: 467–470.PubMedGoogle Scholar
  7. 7.
    White RD, Winkler ML, Higgins CB (1987) MR imaging of pulmonary arterial hypertension and pulmonary emboli.American Journal of Roentgenology,149: 15–21.PubMedGoogle Scholar
  8. 8.
    Bogren HG, Klipstein RH, Mohiaddin RH, Firmin DN, Underwood SR, Rees RSO, Longmore DB (1989) Pulmonary artery distensibility and blood flow patterns: A magnetic resonance study of normal subjects and of patients with pulmonary artery hypertension.Amer Heart J 118: 990–999.PubMedCrossRefGoogle Scholar
  9. 9.
    Posteraro RH, Sostman HD, Spritzer CE, Herfkens RJ (1989) Cine-gradient-refocused MR imaging of central pulmonary emboli.American Journal of Roentgenology,152: 465–468.PubMedGoogle Scholar
  10. 10.
    Thakur ML, Vinitski S, Mitchell DG, Consigny PM, Lin S, DeFulvio J, Rifkin M (1990) MR imaging of pulmonary parenchyma and emboli by paramagnetic and superparamagnetic contrast agents.Mag Reson Imaging 8: 625–630.CrossRefGoogle Scholar
  11. 11.
    Rubin GD, Steiner RM, Pelc NJ, Herfkens RJ (1991) MR Imaging of the pulmonary vasculature: Optimization with a breathold spoiled gradient-echo technique.Radiology 181: 386 (Abstract).Google Scholar
  12. 12.
    Foo TKF, MacFall JR, Hayes CE, Sostman HD, Slayman BE (1992) Pulmonary vasculature: Single breathold MR imaging with phased array coils.Radiology 183: 473–477.PubMedGoogle Scholar
  13. 13.
    Wielopolski PA, Haacke EM, Adler LP (1992) Three dimensional MR pulmonary vascular imaging: Preliminary experience.Radiology 183: 465–472.PubMedGoogle Scholar
  14. 14.
    Haacke EM, Lenz GW, Nelson D (1987) Pseudo-gating: Elimination of periodic motion artifacts in MRI without gating.Mag Reson Med 4: 162–174.CrossRefGoogle Scholar
  15. 15.
    Haacke EM, Patrick JL (1986) Reducing motion artifacts in two-dimensional fourier transform imaging.Mag Reson Imaging 4: 359–376.CrossRefGoogle Scholar
  16. 16.
    Haacke EM, Wielopolski PA, Tkach JA (1991) A comprehensive technical review of short TR, fast, magnetic resonance imaging.Reviews in Magnetic Resonance in Medicine 3(2): 55–170 (Review).Google Scholar
  17. 17.
    Haacke EM, Wielopolski PA, Tkach JA, Modic MT (1990) Steady-state free precession imaging in the presence of motion: Application for improved visualization of the cerebrospinal fluid.Radiology 175: 545–552.PubMedGoogle Scholar
  18. 18.
    Hänicke W, Merboldt KD, Chien D, Gyngell ML, Bruhn H, Frahm J (1990) Signal strength in subsecond FLASH magnetic resonance imaging: The dynamic approach to steady state.Med Phys 17(6): 1004–1010.PubMedCrossRefGoogle Scholar
  19. 19.
    Haase A (1990) SNAPSHOT FLASH MRI. applications toT 1-,T 2-and chemical shift imaging.J Mag Reson 13: 77–89.CrossRefGoogle Scholar
  20. 20.
    Mugler JP III, Brookeman JR (1990) Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE).Mag Reson Med 15: 152–157.CrossRefGoogle Scholar
  21. 21.
    Brix G, Schad LR, Deimling M, Lorenz WJ (1990) Fast and preciset 1 imaging using a TOMROP sequence.Mag Reson Imaging 8: 351–356.CrossRefGoogle Scholar
  22. 22.
    Stehling MK (1992) Improved signal in snapshot FLASH by variable flip angles.Mag Reson Imaging 10: 165–167.CrossRefGoogle Scholar
  23. 23.
    Chien D, Atkinson DJ, Edelman RR (1991) Strategies to improve contrast in TurboFLASH imaging: Reordered phase encoding and K-space segmentation.J Mag Reson Imaging 1: 63–70.CrossRefGoogle Scholar
  24. 24.
    Holsinger AE, Riederer SJ (1990) The importance of phase encoding order in ultra-short TR snapshot MR.Mag Reson Med 16: 481–488.CrossRefGoogle Scholar
  25. 25.
    Mulkern RV, Wong STS, Winalski C, Jolesz FA (1990) Contrast manipulation and artifact assessment of 2D and 3D RARE sequences.Mag Reson Imaging 8: 557–566.CrossRefGoogle Scholar
  26. 26.
    Haacke EM, Masaryk TJ, Wielopolski PA, Zypman FR, Tkach JA, Amartur S, Mitchell J, Clampitt M, Paschal C (1990) Optimizing blood vessel contrast in fast three-dimensional MRI.Mag Reson Med 14: 202–221.CrossRefGoogle Scholar
  27. 27.
    Margosian P, Schmitt F, Purdy D (1986) Faster MR imaging: Imaging with half the data.Health Care Instrum 1: 195–197.Google Scholar
  28. 28.
    Haacke EM, Lindskog ED, Lin W (1991) Partial-Fourier imaging. A fast, iterative, POCS technique capable of local phase recover.J Mag Reson 92: 126–145.Google Scholar
  29. 29.
    Haacke EM, Liang ZP, Izen SH (1989) Constrained reconstruction: A superresolution, optimal signal-to-noise alternative to the fourier transform in magnetic resonance imaging.Med Phys 16(3): 388–397.PubMedCrossRefGoogle Scholar
  30. 30.
    Shioya S, Christman R, Ailion DC (1990) An in vivo NMR imaging determination of multiexponential hahnT 2 of normal lung.Mag Reson Med 16: 40–56.CrossRefGoogle Scholar
  31. 31.
    Bergin CJ, Glover GH, Pauly JM (1991) Lung parenchyma: Magnetic susceptibility in MR imaging.Radiology 180: 845–848.PubMedGoogle Scholar
  32. 32.
    Bergin CJ, Pauly JM, Macovski A (1991) Lung parenchyma: Projection reconstruction MR imaging.Radiology 179: 777–781.PubMedGoogle Scholar
  33. 33.
    Frahm J, Merboldt KD, Bruhn H, Gyngell ML, Hänicke W, Chien D (1990) 0.3 second FLASH MRI of the human heart.Mag Reson Med 13: 150–157.CrossRefGoogle Scholar
  34. 34.
    Chien D, Merboldt KD, Hänicke W, Bruhn H, Gyngell ML, Frahm J (1990) Advances in cardiac applications of subsecond FLASH MRI.Mag Reson Imaging 8: 829–836.CrossRefGoogle Scholar
  35. 35.
    Matthaei MD, Haase A, Henrich D, Duhmke E (1990) Cardiac and vascular imaging with an MR snapshot technique.Radiology 177: 527–532.PubMedGoogle Scholar
  36. 36.
    Lin W, Haacke EM, Smith AS, Clampitt ME (1992) Gadolinium-enhanced high-resolution MR angiography with adaptive vessel tracking: Preliminary results in the intracranial circulation.J Mag Reson Imaging 2: 277–284.CrossRefGoogle Scholar

Copyright information

© Chapman & Hall 1993

Authors and Affiliations

  • Piotr A. Wielopolski
    • 1
  • E. Mark Haacke
    • 1
  • Lee P. Adler
    • 1
  1. 1.Boston and New England DeaconessBeth Israel HospitalClevelandUSA

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