Journal of the American Oil Chemists Society

, Volume 68, Issue 12, pp 935–937

Inhibitory effect of boldine on fish oil oxidation

  • Alfonso Valenzuela
  • Susana Nieto
  • Bruce K. Cassels
  • Hernan Speisky


The antioxidative effect of boldine, an alkaloid extracted fromPeumus boldus Mol. (boldo), was assayed on the spontaneous and on the metal-induced oxidation of fish oil. The inhibitory effect of boldine was compared to those of dl-α tocopherol, the flavonoid quercetin and the synthetic antioxidants butylated hydroxytoluene and butylated hydroxyanisole. Boldine, in all assays, showed a good antioxidative effect, which was comparable to that of quercetin and even better than that of dl-α tocopherol and the synthetic antioxidants. Additive effects were observed when mixtures of boldine and quercetin or dl-α tocopherol were assayed. The present study supports the potential use of boldine as a novel natural antioxidant for fish oil.

Key Words

Boldine boldine as antioxidant fish oil oxidation natural antioxidants. 


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Copyright information

© American Oil Chemists’ Society 1990

Authors and Affiliations

  • Alfonso Valenzuela
    • 1
  • Susana Nieto
    • 1
  • Bruce K. Cassels
    • 3
  • Hernan Speisky
    • 1
  1. 1.Unidad de Bioquimica Farmacologica y Lipidos, INTAUniversidad de ChileSantiagoChile
  2. 2.Unidad de Bioquimica Farmacologica y Lipidos, INTAUniversidad de ChileSantiagoChile
  3. 3.Departamento de Quimica, Facultad de CienciasUniversidad de ChileSantiagoChile

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