In Vitro

, Volume 6, Issue 4, pp 269–273 | Cite as

Nucleohistone content during aging in tissue culture

  • Jon M. Ryan
  • Loyd Y. Quinn
Article

Summary

Nucleohistone was extracted from chick embryo cells at intervals during their in vitro life span. Results showed no significant quantitative change in histone-DNA ratios between old and young cells. Young cells exhibited a cyclic variation in histone-DNA ratio that was not detected in aged cells. Histone-DNA values throught the growth cycle for aged cells were similar to those obtained for young cells in stationary phase. This finding suggests that aged cells resemble young cells in stationary phase with respect to histone-DNA ratio.

Keywords

Chick Embryo Aged Cell Cyclic Variation Young Cell Human Diploid Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Tissue Culture Association 1971

Authors and Affiliations

  • Jon M. Ryan
    • 1
  • Loyd Y. Quinn
    • 1
  1. 1.Department of BacteriologyIowa State UniversityAmes

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